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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3M1
All Species:
40.91
Human Site:
Y180
Identified Species:
64.29
UniProt:
Q9Y2T2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2T2
NP_036227.1
418
46939
Y180
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
I
Chimpanzee
Pan troglodytes
XP_001141331
436
49226
Y180
K
Y
T
N
N
E
A
Y
F
D
V
I
E
E
I
Rhesus Macaque
Macaca mulatta
XP_001098843
418
46925
Y180
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
I
Dog
Lupus familis
XP_546170
477
52895
Y239
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKC8
418
46918
Y180
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
I
Rat
Rattus norvegicus
P53676
418
46963
Y180
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506462
418
46967
Y180
K
Y
T
N
N
E
A
Y
F
D
V
I
E
E
I
Chicken
Gallus gallus
Q5ZMP7
418
46954
Y180
K
Y
T
N
N
E
A
Y
F
D
V
I
E
E
I
Frog
Xenopus laevis
Q801Q8
435
49666
E179
E
L
F
L
D
V
L
E
S
V
N
L
L
M
S
Zebra Danio
Brachydanio rerio
Q6NWK2
436
49641
E179
E
L
F
L
D
V
L
E
S
V
N
L
L
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788873
415
46777
Y178
R
Y
T
N
N
E
A
Y
F
D
V
I
E
E
V
Honey Bee
Apis mellifera
XP_624899
417
47249
Y180
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
V
Nematode Worm
Caenorhab. elegans
P35602
422
48210
L181
V
I
E
S
V
N
M
L
A
S
A
N
G
T
V
Sea Urchin
Strong. purpuratus
XP_788000
416
46931
A179
V
K
Y
T
N
N
E
A
Y
F
D
V
I
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
I182
K
N
E
A
F
L
D
I
V
E
S
I
N
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
99.7
87.6
N.A.
99.5
98.8
N.A.
97.3
95.4
25.7
25.4
N.A.
69.1
71.5
26
74.8
Protein Similarity:
100
90.8
99.7
87.6
N.A.
99.7
99.5
N.A.
99.5
97.8
49.4
49
N.A.
85.1
86.1
51.9
89.7
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
93.3
0
0
N.A.
80
93.3
0
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
20
20
N.A.
100
100
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
67
7
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
14
0
7
0
0
67
7
0
0
0
0
% D
% Glu:
14
0
14
0
0
67
7
14
0
7
0
0
67
74
7
% E
% Phe:
0
0
14
0
7
0
0
0
67
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
7
0
0
0
34
7
0
54
% I
% Lys:
67
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
14
0
14
0
7
14
7
0
0
0
14
14
0
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
20
0
% M
% Asn:
0
7
0
67
74
14
0
0
0
0
14
7
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
0
0
0
0
14
7
7
0
0
0
14
% S
% Thr:
0
0
67
7
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
14
0
0
0
7
14
0
0
7
14
67
47
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
67
7
0
0
0
0
67
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _