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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GDA All Species: 30.91
Human Site: Y258 Identified Species: 56.67
UniProt: Q9Y2T3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2T3 NP_004284.1 454 51003 Y258 V K N L Y P S Y K N Y T S V Y
Chimpanzee Pan troglodytes XP_528320 573 63340 Y360 V K N L Y P S Y K N Y T S V Y
Rhesus Macaque Macaca mulatta XP_001095322 490 54864 Y258 V K N L Y P N Y K N H T D V Y
Dog Lupus familis XP_541285 573 62781 Y377 V K S L F Y D Y K N Y T D V Y
Cat Felis silvestris
Mouse Mus musculus Q9R111 454 50995 Y258 V K S L Y P S Y K N Y T D V Y
Rat Rattus norvegicus Q9WTT6 454 50998 Y258 V K S L Y P G Y K N Y T D V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505734 465 52735 Y269 V K E L F P N Y K N Y T D V Y
Chicken Gallus gallus XP_424835 489 54761 Y297 V E N M F P A Y Q N Y T D L Y
Frog Xenopus laevis NP_001083074 376 42513 Y198 E A M Q N M K Y D R V K P I I
Zebra Danio Brachydanio rerio NP_001018510 450 50314 C259 V K R L F P D C R S Y T D V Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649439 448 48866 S249 V K G I F K T S Y A G A Y D E
Honey Bee Apis mellifera XP_001123002 404 45159 D226 S S Y A A V Y D N A G L L T N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q07729 489 55185 C276 V Q D L F P E C E S Y T D V Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.7 88.9 69.8 N.A. 90.7 90.3 N.A. 73.9 62.9 50 58.5 N.A. 43.1 43.6 N.A. N.A.
Protein Similarity: 100 79 91.4 74.5 N.A. 95.8 95.1 N.A. 83.2 75.8 63 76.2 N.A. 59.6 63 N.A. N.A.
P-Site Identity: 100 100 80 66.6 N.A. 86.6 80 N.A. 73.3 53.3 6.6 53.3 N.A. 13.3 0 N.A. N.A.
P-Site Similarity: 100 100 93.3 80 N.A. 93.3 86.6 N.A. 86.6 93.3 13.3 73.3 N.A. 33.3 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 53.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 8 0 0 16 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 16 8 8 0 0 0 62 8 0 % D
% Glu: 8 8 8 0 0 0 8 0 8 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 47 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 8 0 0 0 16 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 8 % I
% Lys: 0 70 0 0 0 8 8 0 54 0 0 8 0 0 0 % K
% Leu: 0 0 0 70 0 0 0 0 0 0 0 8 8 8 0 % L
% Met: 0 0 8 8 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 31 0 8 0 16 0 8 62 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 70 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 8 0 8 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 8 8 0 0 0 0 0 % R
% Ser: 8 8 24 0 0 0 24 8 0 16 0 0 16 0 0 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 77 0 8 0 % T
% Val: 85 0 0 0 0 8 0 0 0 0 8 0 0 70 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 39 8 8 70 8 0 70 0 8 0 77 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _