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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR52 All Species: 13.94
Human Site: S246 Identified Species: 30.67
UniProt: Q9Y2T5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2T5 NP_005675.3 361 41354 S246 D R R A R F P S H E V D S S R
Chimpanzee Pan troglodytes XP_514013 361 41368 S246 D R R A R F P S H E V D S S R
Rhesus Macaque Macaca mulatta Q28524 418 44639 P247 W E L G R F P P E E S S P A L
Dog Lupus familis XP_851557 352 39896 G243 S G E T G E T G E V Q S C P D
Cat Felis silvestris
Mouse Mus musculus P0C5J4 361 41325 S246 D R R A R F P S H E V E A S R
Rat Rattus norvegicus P10608 418 46873 S254 Q V E Q D G R S G H G L R S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515554 361 41224 S246 D R R A R F P S H E V D A A G
Chicken Gallus gallus O13076 340 37753 H231 T T L Q K E V H A A K S L A I
Frog Xenopus laevis NP_001083418 406 46234 L272 I I M G T F T L C W L P F F I
Zebra Danio Brachydanio rerio Q1JPS6 500 54471 G269 E I R E L D C G E T H K V Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186543 430 48225 A289 S E M M F K S A S Q R E G T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 23.4 66.7 N.A. 95.5 23.4 N.A. 91.9 25.2 23.8 21.6 N.A. N.A. N.A. N.A. 30.2
Protein Similarity: 100 100 39.7 77.8 N.A. 97.7 41.3 N.A. 96.1 40.7 42.8 37 N.A. N.A. N.A. N.A. 46.2
P-Site Identity: 100 100 26.6 0 N.A. 86.6 13.3 N.A. 80 0 6.6 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 33.3 0 N.A. 100 13.3 N.A. 93.3 13.3 13.3 13.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 37 0 0 0 10 10 10 0 0 19 28 0 % A
% Cys: 0 0 0 0 0 0 10 0 10 0 0 0 10 0 0 % C
% Asp: 37 0 0 0 10 10 0 0 0 0 0 28 0 0 10 % D
% Glu: 10 19 19 10 0 19 0 0 28 46 0 19 0 0 10 % E
% Phe: 0 0 0 0 10 55 0 0 0 0 0 0 10 10 0 % F
% Gly: 0 10 0 19 10 10 0 19 10 0 10 0 10 0 10 % G
% His: 0 0 0 0 0 0 0 10 37 10 10 0 0 0 0 % H
% Ile: 10 19 0 0 0 0 0 0 0 0 0 0 0 0 19 % I
% Lys: 0 0 0 0 10 10 0 0 0 0 10 10 0 0 0 % K
% Leu: 0 0 19 0 10 0 0 10 0 0 10 10 10 0 10 % L
% Met: 0 0 19 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 46 10 0 0 0 10 10 10 0 % P
% Gln: 10 0 0 19 0 0 0 0 0 10 10 0 0 0 0 % Q
% Arg: 0 37 46 0 46 0 10 0 0 0 10 0 10 0 37 % R
% Ser: 19 0 0 0 0 0 10 46 10 0 10 28 19 37 10 % S
% Thr: 10 10 0 10 10 0 19 0 0 10 0 0 0 10 0 % T
% Val: 0 10 0 0 0 0 10 0 0 10 37 0 10 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _