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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K2
All Species:
18.18
Human Site:
S349
Identified Species:
57.14
UniProt:
Q9Y2U5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2U5
NP_006600.3
619
69741
S349
D
I
S
P
P
S
R
S
P
R
A
P
T
N
W
Chimpanzee
Pan troglodytes
XP_001137266
619
69745
S349
D
I
S
P
P
S
R
S
P
R
A
P
T
N
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852274
619
69735
S349
D
I
S
P
P
S
R
S
P
R
A
P
T
N
W
Cat
Felis silvestris
Mouse
Mus musculus
Q61083
619
69555
S349
D
I
S
P
P
S
R
S
P
R
A
P
T
N
W
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514112
322
36091
G71
L
L
G
Q
G
A
F
G
R
V
Y
L
C
Y
D
Chicken
Gallus gallus
XP_422075
623
70135
S353
D
I
S
P
P
S
R
S
P
R
A
P
T
N
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782621
389
43041
V138
L
G
Q
G
A
F
G
V
V
Y
V
C
Y
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23561
717
80702
H393
E
S
G
E
E
E
D
H
D
F
F
G
E
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98.8
N.A.
95.8
N.A.
N.A.
49.1
91
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
39.5
Protein Similarity:
100
100
N.A.
99.1
N.A.
97.9
N.A.
N.A.
50.7
95.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
0
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
13.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
13
0
0
0
0
63
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
13
13
0
0
% C
% Asp:
63
0
0
0
0
0
13
0
13
0
0
0
0
25
13
% D
% Glu:
13
0
0
13
13
13
0
0
0
0
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
13
13
0
0
13
13
0
0
0
0
% F
% Gly:
0
13
25
13
13
0
13
13
0
0
0
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
63
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
13
0
0
0
0
0
0
0
0
0
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
0
% N
% Pro:
0
0
0
63
63
0
0
0
63
0
0
63
0
0
0
% P
% Gln:
0
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
63
0
13
63
0
0
0
0
0
% R
% Ser:
0
13
63
0
0
63
0
63
0
0
0
0
0
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
63
0
0
% T
% Val:
0
0
0
0
0
0
0
13
13
13
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
63
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
13
0
13
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _