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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K2
All Species:
17.27
Human Site:
S606
Identified Species:
54.29
UniProt:
Q9Y2U5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2U5
NP_006600.3
619
69741
S606
V
E
A
K
L
R
P
S
A
D
E
L
L
R
H
Chimpanzee
Pan troglodytes
XP_001137266
619
69745
S606
V
E
A
K
L
R
P
S
A
D
E
L
L
R
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852274
619
69735
S606
I
E
A
K
L
R
P
S
A
D
E
L
L
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q61083
619
69555
S606
V
E
A
K
L
R
P
S
A
E
E
L
L
R
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514112
322
36091
A310
E
V
K
L
R
P
S
A
D
E
L
L
R
H
T
Chicken
Gallus gallus
XP_422075
623
70135
F610
I
E
A
K
L
R
P
F
A
D
E
L
L
R
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782621
389
43041
L377
D
R
P
S
A
A
E
L
L
R
H
N
F
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23561
717
80702
S702
L
D
Y
Q
Y
R
P
S
A
L
E
L
L
Q
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98.8
N.A.
95.8
N.A.
N.A.
49.1
91
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
39.5
Protein Similarity:
100
100
N.A.
99.1
N.A.
97.9
N.A.
N.A.
50.7
95.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
N.A.
N.A.
6.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
20
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
63
0
13
13
0
13
75
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
13
0
0
0
0
0
0
13
50
0
0
0
0
0
% D
% Glu:
13
63
0
0
0
0
13
0
0
25
75
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
13
0
0
0
0
13
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
0
0
13
75
% H
% Ile:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
63
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
0
0
13
63
0
0
13
13
13
13
88
75
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% N
% Pro:
0
0
13
0
0
13
75
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
13
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
0
13
0
0
13
75
0
0
0
13
0
0
13
63
13
% R
% Ser:
0
0
0
13
0
0
13
63
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% T
% Val:
38
13
0
0
0
0
0
0
0
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _