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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEMD3
All Species:
9.09
Human Site:
S259
Identified Species:
28.57
UniProt:
Q9Y2U8
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2U8
NP_055134.2
911
99997
S259
Y
S
C
R
E
N
Y
S
D
S
E
E
E
D
D
Chimpanzee
Pan troglodytes
XP_509197
911
100009
S259
Y
S
C
R
E
N
Y
S
D
S
E
E
E
D
D
Rhesus Macaque
Macaca mulatta
XP_001116983
909
99874
S259
Y
S
C
R
E
N
Y
S
D
S
E
E
E
D
D
Dog
Lupus familis
XP_850494
721
79778
V125
A
G
R
P
D
T
S
V
Q
G
G
G
G
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU40
921
100288
E266
H
Y
S
D
S
E
E
E
E
E
E
G
E
E
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416073
385
43948
Frog
Xenopus laevis
NP_001082578
781
88447
R184
C
R
T
M
N
G
S
R
H
S
Y
C
R
D
Y
Zebra Danio
Brachydanio rerio
NP_001038329
841
93951
P242
S
P
P
A
S
S
S
P
Y
R
S
A
W
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
69.2
N.A.
82.3
N.A.
N.A.
N.A.
34.4
54.2
50.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99
72.6
N.A.
87.3
N.A.
N.A.
N.A.
39
65.5
63.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
20
N.A.
N.A.
N.A.
0
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
40
N.A.
N.A.
N.A.
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
13
0
0
0
0
0
0
0
13
0
0
13
% A
% Cys:
13
0
38
0
0
0
0
0
0
0
0
13
0
0
0
% C
% Asp:
0
0
0
13
13
0
0
0
38
0
0
0
0
50
50
% D
% Glu:
0
0
0
0
38
13
13
13
13
13
50
38
50
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
0
13
0
0
0
13
13
25
13
0
0
% G
% His:
13
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
38
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
13
13
0
0
0
13
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
13
13
38
0
0
0
13
0
13
0
0
13
0
0
% R
% Ser:
13
38
13
0
25
13
38
38
0
50
13
0
0
25
13
% S
% Thr:
0
0
13
0
0
13
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% W
% Tyr:
38
13
0
0
0
0
38
0
13
0
13
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _