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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC2
All Species:
10.3
Human Site:
S23
Identified Species:
22.67
UniProt:
Q9Y2U9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2U9
NP_055130.1
406
46099
S23
P
A
F
E
S
Y
E
S
M
E
L
A
C
P
A
Chimpanzee
Pan troglodytes
XP_509933
307
34866
Rhesus Macaque
Macaca mulatta
XP_001098629
406
46128
S23
P
A
F
E
S
Y
E
S
M
E
L
A
C
P
A
Dog
Lupus familis
XP_537436
406
46064
S23
P
A
Y
E
S
Y
E
S
M
E
L
A
C
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q4G5Y1
406
45939
A23
P
A
F
E
N
Y
E
A
M
E
L
A
C
P
A
Rat
Rattus norvegicus
Q3KRE6
406
45907
A23
P
A
F
E
G
Y
E
A
M
E
L
A
C
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514104
407
45986
P24
P
A
D
E
S
S
E
P
L
E
P
A
S
P
A
Chicken
Gallus gallus
Q5ZJ37
371
40041
Frog
Xenopus laevis
Q5U580
411
46740
S24
L
S
G
R
A
A
G
S
K
K
K
V
R
W
F
Zebra Danio
Brachydanio rerio
Q6GQN7
351
38328
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002318573
398
44479
Q11
E
R
V
Q
Q
Q
L
Q
Q
G
V
A
I
E
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
99.5
98.7
N.A.
96.5
97
N.A.
88.9
22.6
21.6
21.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.1
99.7
99.5
N.A.
98.5
98.7
N.A.
94.8
36.4
35.7
37.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
86.6
86.6
N.A.
60
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
93.3
N.A.
66.6
0
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
0
0
10
10
0
19
0
0
0
64
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
46
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
55
0
0
55
0
0
55
0
0
0
10
10
% E
% Phe:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
10
0
10
0
10
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
10
0
10
0
46
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
46
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
55
0
0
0
0
0
0
10
0
0
10
0
0
55
0
% P
% Gln:
0
0
0
10
10
10
0
10
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
0
0
37
10
0
37
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
10
0
0
46
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _