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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC2
All Species:
22.73
Human Site:
S272
Identified Species:
50
UniProt:
Q9Y2U9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2U9
NP_055130.1
406
46099
S272
P
V
G
R
S
W
H
S
L
T
P
V
S
S
D
Chimpanzee
Pan troglodytes
XP_509933
307
34866
W183
E
F
D
E
T
S
F
W
N
S
S
H
P
R
G
Rhesus Macaque
Macaca mulatta
XP_001098629
406
46128
S272
P
V
G
R
S
W
H
S
L
T
P
V
S
S
D
Dog
Lupus familis
XP_537436
406
46064
S272
P
V
G
R
S
W
H
S
L
T
P
V
S
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q4G5Y1
406
45939
S272
P
V
G
R
S
W
H
S
L
T
P
V
S
S
D
Rat
Rattus norvegicus
Q3KRE6
406
45907
S272
P
V
G
R
S
W
H
S
L
T
P
V
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514104
407
45986
S273
P
V
G
R
S
W
H
S
L
T
P
V
S
S
D
Chicken
Gallus gallus
Q5ZJ37
371
40041
A247
G
R
A
S
H
S
S
A
V
F
K
D
H
L
Y
Frog
Xenopus laevis
Q5U580
411
46740
G277
D
I
P
T
K
P
H
G
N
L
G
F
P
A
A
Zebra Danio
Brachydanio rerio
Q6GQN7
351
38328
H227
G
M
S
G
E
K
F
H
S
D
M
F
T
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002318573
398
44479
D261
T
D
A
Q
N
L
Y
D
D
L
H
M
L
N
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
99.5
98.7
N.A.
96.5
97
N.A.
88.9
22.6
21.6
21.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.1
99.7
99.5
N.A.
98.5
98.7
N.A.
94.8
36.4
35.7
37.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
13.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
0
10
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
0
0
0
0
10
10
10
0
10
0
0
55
% D
% Glu:
10
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
19
0
0
10
0
19
0
0
0
% F
% Gly:
19
0
55
10
0
0
0
10
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
10
0
64
10
0
0
10
10
10
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
55
19
0
0
10
19
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
19
0
0
0
0
10
10
% N
% Pro:
55
0
10
0
0
10
0
0
0
0
55
0
19
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
55
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
10
10
55
19
10
55
10
10
10
0
55
55
0
% S
% Thr:
10
0
0
10
10
0
0
0
0
55
0
0
10
0
0
% T
% Val:
0
55
0
0
0
0
0
0
10
0
0
55
0
0
10
% V
% Trp:
0
0
0
0
0
55
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _