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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHDC2 All Species: 22.73
Human Site: S90 Identified Species: 50
UniProt: Q9Y2U9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2U9 NP_055130.1 406 46099 S90 T E G D V P P S M S G S C A V
Chimpanzee Pan troglodytes XP_509933 307 34866
Rhesus Macaque Macaca mulatta XP_001098629 406 46128 S90 T E G D V P P S M S G S C A V
Dog Lupus familis XP_537436 406 46064 S90 T E G D V P P S M S G S C A V
Cat Felis silvestris
Mouse Mus musculus Q4G5Y1 406 45939 S90 T E G D V P P S M S G S C A V
Rat Rattus norvegicus Q3KRE6 406 45907 S90 T E G D V P P S M S G S C A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514104 407 45986 S91 T E G D V P P S M S G S C A V
Chicken Gallus gallus Q5ZJ37 371 40041 G69 D A H F V E L G A H L W A P A
Frog Xenopus laevis Q5U580 411 46740 N91 D E S G G P E N E D Y P L F R
Zebra Danio Brachydanio rerio Q6GQN7 351 38328 G49 A H H H D E D G G G K G K I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002318573 398 44479 R78 N G T L P V P R D S H S C T T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.6 99.5 98.7 N.A. 96.5 97 N.A. 88.9 22.6 21.6 21.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 75.1 99.7 99.5 N.A. 98.5 98.7 N.A. 94.8 36.4 35.7 37.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 6.6 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 100 6.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 26.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 44.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 10 0 0 0 10 55 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 64 0 0 % C
% Asp: 19 0 0 55 10 0 10 0 10 10 0 0 0 0 0 % D
% Glu: 0 64 0 0 0 19 10 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 10 55 10 10 0 0 19 10 10 55 10 0 0 0 % G
% His: 0 10 19 10 0 0 0 0 0 10 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % K
% Leu: 0 0 0 10 0 0 10 0 0 0 10 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 55 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 64 64 0 0 0 0 10 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % R
% Ser: 0 0 10 0 0 0 0 55 0 64 0 64 0 0 0 % S
% Thr: 55 0 10 0 0 0 0 0 0 0 0 0 0 10 10 % T
% Val: 0 0 0 0 64 10 0 0 0 0 0 0 0 0 64 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _