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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC2
All Species:
22.12
Human Site:
Y59
Identified Species:
48.67
UniProt:
Q9Y2U9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2U9
NP_055130.1
406
46099
Y59
S
N
Q
V
R
G
L
Y
D
F
Y
L
P
R
E
Chimpanzee
Pan troglodytes
XP_509933
307
34866
Rhesus Macaque
Macaca mulatta
XP_001098629
406
46128
Y59
S
N
Q
V
R
G
L
Y
D
F
Y
L
P
R
E
Dog
Lupus familis
XP_537436
406
46064
Y59
S
N
Q
V
R
G
L
Y
D
F
Y
L
P
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q4G5Y1
406
45939
Y59
S
N
Q
V
R
G
L
Y
D
F
Y
L
P
R
E
Rat
Rattus norvegicus
Q3KRE6
406
45907
Y59
S
N
Q
V
R
G
L
Y
D
F
Y
L
P
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514104
407
45986
Y60
N
A
Q
V
R
G
F
Y
D
F
Y
L
P
R
D
Chicken
Gallus gallus
Q5ZJ37
371
40041
C38
R
G
R
V
G
H
G
C
L
F
V
P
G
G
S
Frog
Xenopus laevis
Q5U580
411
46740
A60
E
G
R
R
S
P
P
A
R
S
G
H
R
C
V
Zebra Danio
Brachydanio rerio
Q6GQN7
351
38328
W18
Q
K
P
Q
N
R
H
W
Y
V
L
E
P
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002318573
398
44479
K47
Y
V
F
G
G
Y
G
K
D
N
C
Q
T
N
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
99.5
98.7
N.A.
96.5
97
N.A.
88.9
22.6
21.6
21.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.1
99.7
99.5
N.A.
98.5
98.7
N.A.
94.8
36.4
35.7
37.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
73.3
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
86.6
20
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
64
0
0
0
0
0
10
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
46
% E
% Phe:
0
0
10
0
0
0
10
0
0
64
0
0
0
0
0
% F
% Gly:
0
19
0
10
19
55
19
0
0
0
10
0
10
10
10
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
46
0
10
0
10
55
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
46
0
0
10
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
0
0
10
0
0
10
10
0
0
0
0
10
64
0
0
% P
% Gln:
10
0
55
10
0
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
10
0
19
10
55
10
0
0
10
0
0
0
10
55
0
% R
% Ser:
46
0
0
0
10
0
0
0
0
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% T
% Val:
0
10
0
64
0
0
0
0
0
10
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
55
10
0
55
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _