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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAX All Species: 14.85
Human Site: Y274 Identified Species: 27.22
UniProt: Q9Y2V3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2V3 NP_038463.2 346 36676 Y274 A Q S L P A S Y T P P P P P P
Chimpanzee Pan troglodytes A2T711 184 20085 P133 P P A V P G L P R L L G P G P
Rhesus Macaque Macaca mulatta XP_001087324 347 36717 Y274 A Q S L P A S Y T P P P P P P
Dog Lupus familis XP_852642 288 30990 L237 V R V Q P I G L P P T Q P P A
Cat Felis silvestris
Mouse Mus musculus O35602 342 36378 Y274 G Q G L P A S Y T P P P P F L
Rat Rattus norvegicus Q9JLT7 342 36319 Y274 G Q G L P A S Y T P P P P F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516357 231 25819 Q180 P S M A Q P L Q P M A P T S Y
Chicken Gallus gallus Q9PVX0 317 34038 P249 G L P A S Y T P P P F L N S P
Frog Xenopus laevis O42567 325 36295 Y255 P T S L P G S Y T P P P F I N
Zebra Danio Brachydanio rerio O42357 327 37134 P258 G P G Q S L Q P T Y T A H P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2Q1 873 92878 A762 S Q S S S S S A S L E C S G P
Honey Bee Apis mellifera XP_001119966 282 30412 L231 G S A V P G G L S A G M T S I
Nematode Worm Caenorhab. elegans Q94398 276 31563 T225 E S P Q T P S T S S P F I S E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.1 98.2 41.3 N.A. 85.2 86.4 N.A. 46.5 67 62.1 48.8 N.A. 24.2 37.5 25.7 N.A.
Protein Similarity: 100 42.4 98.5 50.5 N.A. 88.1 89.5 N.A. 53.1 74.2 70.5 60.4 N.A. 28.6 46.5 36.4 N.A.
P-Site Identity: 100 20 100 26.6 N.A. 73.3 73.3 N.A. 6.6 13.3 60 13.3 N.A. 26.6 6.6 13.3 N.A.
P-Site Similarity: 100 33.3 100 33.3 N.A. 73.3 73.3 N.A. 6.6 20 60 13.3 N.A. 46.6 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 16 16 0 31 0 8 0 8 8 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 8 8 16 0 % F
% Gly: 39 0 24 0 0 24 16 0 0 0 8 8 0 16 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 39 0 8 16 16 0 16 8 8 0 0 16 % L
% Met: 0 0 8 0 0 0 0 0 0 8 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % N
% Pro: 24 16 16 0 62 16 0 24 24 54 47 47 47 31 39 % P
% Gln: 0 39 0 24 8 0 8 8 0 0 0 8 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 8 24 31 8 24 8 54 0 24 8 0 0 8 31 0 % S
% Thr: 0 8 0 0 8 0 8 8 47 0 16 0 16 0 0 % T
% Val: 8 0 8 16 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 39 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _