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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG6
All Species:
25.15
Human Site:
S158
Identified Species:
42.56
UniProt:
Q9Y2V7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2V7
NP_001138551.1
657
73279
S158
Q
V
A
D
A
F
L
S
K
F
Q
L
T
S
D
Chimpanzee
Pan troglodytes
XP_509639
657
73244
S158
Q
V
A
D
A
F
L
S
K
F
Q
L
T
S
D
Rhesus Macaque
Macaca mulatta
XP_001088372
657
73195
S158
Q
V
A
D
A
F
L
S
K
F
Q
L
T
S
D
Dog
Lupus familis
XP_534488
657
73161
S158
Q
V
A
D
A
F
L
S
K
F
Q
L
T
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3I3
657
73021
A158
Q
V
V
D
A
F
L
A
K
F
Q
L
T
S
D
Rat
Rattus norvegicus
Q68FP9
657
72938
S158
Q
V
A
D
A
F
L
S
K
F
Q
L
T
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512635
670
74494
S171
Q
I
A
D
A
F
L
S
K
F
Q
L
T
S
D
Chicken
Gallus gallus
XP_417082
643
72198
G158
D
E
M
N
L
L
R
G
T
K
D
E
P
I
T
Frog
Xenopus laevis
NP_001084743
648
72605
E157
K
F
Q
L
T
S
D
E
M
N
I
L
R
G
T
Zebra Danio
Brachydanio rerio
XP_001918856
305
34143
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V564
630
71187
K154
Q
L
L
Y
G
A
A
K
D
A
P
I
V
A
D
Honey Bee
Apis mellifera
XP_393779
627
71085
E151
I
L
H
G
S
T
R
E
S
P
I
T
E
E
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784841
530
59722
E54
T
R
D
G
Q
L
Q
E
N
F
F
H
S
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S4D8
713
79358
T166
K
L
L
S
T
F
K
T
H
F
I
L
T
Q
D
Conservation
Percent
Protein Identity:
100
99.8
98.4
94.9
N.A.
91.1
92
N.A.
88.5
86.6
84
36.3
N.A.
40
44.9
N.A.
49.6
Protein Similarity:
100
99.8
99.2
97.8
N.A.
96
96.9
N.A.
92.6
92.8
92.6
40.9
N.A.
61.9
66.8
N.A.
65.7
P-Site Identity:
100
100
100
100
N.A.
86.6
100
N.A.
93.3
0
6.6
0
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
100
6.6
13.3
0
N.A.
33.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
27.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
47.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
43
0
50
8
8
8
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
50
0
0
8
0
8
0
8
0
0
0
65
% D
% Glu:
0
8
0
0
0
0
0
22
0
0
0
8
8
8
0
% E
% Phe:
0
8
0
0
0
58
0
0
0
65
8
0
0
0
8
% F
% Gly:
0
0
0
15
8
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
22
8
0
8
0
% I
% Lys:
15
0
0
0
0
0
8
8
50
8
0
0
0
0
0
% K
% Leu:
0
22
15
8
8
15
50
0
0
0
0
65
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% P
% Gln:
58
0
8
0
8
0
8
0
0
0
50
0
0
8
0
% Q
% Arg:
0
8
0
0
0
0
15
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
8
8
8
0
43
8
0
0
0
8
50
0
% S
% Thr:
8
0
0
0
15
8
0
8
8
0
0
8
58
0
22
% T
% Val:
0
43
8
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _