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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG6
All Species:
36.36
Human Site:
T518
Identified Species:
61.54
UniProt:
Q9Y2V7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2V7
NP_001138551.1
657
73279
T518
T
L
A
L
F
E
F
T
D
R
R
L
E
M
L
Chimpanzee
Pan troglodytes
XP_509639
657
73244
T518
T
L
A
L
F
E
F
T
D
R
R
L
E
M
L
Rhesus Macaque
Macaca mulatta
XP_001088372
657
73195
T518
T
L
A
L
F
E
F
T
D
R
R
L
E
M
L
Dog
Lupus familis
XP_534488
657
73161
T518
T
L
A
L
F
E
F
T
D
R
R
L
E
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3I3
657
73021
T518
T
L
A
L
F
E
F
T
D
R
R
L
E
M
L
Rat
Rattus norvegicus
Q68FP9
657
72938
T518
T
L
A
L
F
E
F
T
D
R
R
L
E
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512635
670
74494
T531
T
L
A
L
F
E
F
T
D
K
R
L
E
M
L
Chicken
Gallus gallus
XP_417082
643
72198
T504
T
L
A
L
F
E
F
T
D
K
R
L
E
M
L
Frog
Xenopus laevis
NP_001084743
648
72605
T509
T
L
A
L
F
E
F
T
D
K
R
L
E
M
L
Zebra Danio
Brachydanio rerio
XP_001918856
305
34143
Q169
V
L
P
L
D
A
R
Q
A
D
F
A
Q
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V564
630
71187
V494
H
M
Q
S
S
L
A
V
Y
E
Y
M
D
E
R
Honey Bee
Apis mellifera
XP_393779
627
71085
R491
L
Y
E
Y
M
D
Q
R
L
E
R
L
Q
A
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784841
530
59722
R394
L
Y
E
Y
T
D
Q
R
L
E
M
L
E
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S4D8
713
79358
V556
T
L
S
G
F
T
F
V
R
K
Y
A
A
D
I
Conservation
Percent
Protein Identity:
100
99.8
98.4
94.9
N.A.
91.1
92
N.A.
88.5
86.6
84
36.3
N.A.
40
44.9
N.A.
49.6
Protein Similarity:
100
99.8
99.2
97.8
N.A.
96
96.9
N.A.
92.6
92.8
92.6
40.9
N.A.
61.9
66.8
N.A.
65.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
20
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
33.3
N.A.
20
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
27.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
47.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
65
0
0
8
8
0
8
0
0
15
8
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
15
0
0
65
8
0
0
8
8
0
% D
% Glu:
0
0
15
0
0
65
0
0
0
22
0
0
72
8
0
% E
% Phe:
0
0
0
0
72
0
72
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% K
% Leu:
15
79
0
72
0
8
0
0
15
0
0
79
0
0
72
% L
% Met:
0
8
0
0
8
0
0
0
0
0
8
8
0
65
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
15
8
0
0
0
0
15
0
15
% Q
% Arg:
0
0
0
0
0
0
8
15
8
43
72
0
0
0
8
% R
% Ser:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
72
0
0
0
8
8
0
65
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
15
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
15
0
0
0
0
8
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _