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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG6
All Species:
35.76
Human Site:
Y588
Identified Species:
60.51
UniProt:
Q9Y2V7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2V7
NP_001138551.1
657
73279
Y588
A
M
V
Q
F
D
R
Y
L
S
A
P
D
N
L
Chimpanzee
Pan troglodytes
XP_509639
657
73244
Y588
A
M
V
Q
F
D
R
Y
L
S
A
P
D
N
L
Rhesus Macaque
Macaca mulatta
XP_001088372
657
73195
Y588
A
M
V
Q
F
D
R
Y
L
S
A
P
D
N
L
Dog
Lupus familis
XP_534488
657
73161
Y588
A
M
V
Q
F
D
R
Y
L
S
A
P
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3I3
657
73021
Y588
A
M
A
Q
F
D
R
Y
L
S
A
P
D
H
L
Rat
Rattus norvegicus
Q68FP9
657
72938
Y588
A
M
A
Q
F
D
R
Y
L
S
A
P
D
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512635
670
74494
Y601
A
M
A
Q
F
D
R
Y
L
A
A
P
D
N
L
Chicken
Gallus gallus
XP_417082
643
72198
Y574
A
M
A
Q
F
D
R
Y
L
S
A
P
D
S
L
Frog
Xenopus laevis
NP_001084743
648
72605
Y579
A
M
V
Q
F
D
R
Y
L
S
A
P
D
N
L
Zebra Danio
Brachydanio rerio
XP_001918856
305
34143
T237
Q
I
E
A
H
L
D
T
L
I
N
E
Q
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V564
630
71187
L562
K
M
D
A
F
L
E
L
P
D
V
L
L
L
P
Honey Bee
Apis mellifera
XP_393779
627
71085
M559
K
L
E
A
F
L
V
M
P
D
V
L
L
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784841
530
59722
L462
I
N
R
F
D
S
F
L
G
S
P
D
S
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S4D8
713
79358
F630
S
S
Q
K
L
D
D
F
L
P
S
A
L
I
D
Conservation
Percent
Protein Identity:
100
99.8
98.4
94.9
N.A.
91.1
92
N.A.
88.5
86.6
84
36.3
N.A.
40
44.9
N.A.
49.6
Protein Similarity:
100
99.8
99.2
97.8
N.A.
96
96.9
N.A.
92.6
92.8
92.6
40.9
N.A.
61.9
66.8
N.A.
65.7
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
86.6
86.6
100
6.6
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
100
13.3
N.A.
13.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
27.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
47.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
65
0
29
22
0
0
0
0
0
8
65
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
72
15
0
0
15
0
8
65
0
8
% D
% Glu:
0
0
15
0
0
0
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
8
79
0
8
8
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
15
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
15
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
8
22
0
15
79
0
0
15
22
15
65
% L
% Met:
0
72
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
36
0
% N
% Pro:
0
0
0
0
0
0
0
0
15
8
8
65
0
0
15
% P
% Gln:
8
0
8
65
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
8
0
0
0
65
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
0
8
0
0
0
65
8
0
8
15
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% T
% Val:
0
0
36
0
0
0
8
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _