KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED16
All Species:
22.73
Human Site:
S310
Identified Species:
50
UniProt:
Q9Y2X0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X0
NP_005472.2
877
96793
S310
S
S
I
V
E
C
W
S
L
R
K
E
G
L
P
Chimpanzee
Pan troglodytes
XP_512222
695
76224
F171
F
S
P
S
L
T
L
F
G
G
K
P
M
E
G
Rhesus Macaque
Macaca mulatta
XP_001117192
1051
116709
S310
S
S
I
V
E
C
W
S
L
R
K
E
G
L
P
Dog
Lupus familis
XP_542212
829
91830
S298
S
S
I
V
E
C
W
S
L
R
K
E
G
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF3
828
91753
S298
S
S
L
V
E
C
W
S
L
R
K
E
G
L
P
Rat
Rattus norvegicus
NP_001100238
865
95318
S335
S
S
L
V
E
C
W
S
L
R
K
E
G
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510303
330
37309
Chicken
Gallus gallus
XP_418220
830
92811
S299
N
S
I
V
E
C
W
S
L
R
K
E
G
L
P
Frog
Xenopus laevis
Q566H4
697
77784
V173
E
G
W
I
A
V
T
V
S
G
L
V
T
V
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W278
818
89961
G294
S
Q
T
S
I
F
L
G
P
L
D
G
R
R
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177975
481
52996
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
77.4
88.8
N.A.
86.6
88
N.A.
32
79.4
66.2
N.A.
N.A.
26
N.A.
N.A.
25
Protein Similarity:
100
72.8
79.3
90.9
N.A.
89.8
91.1
N.A.
33.9
87.2
72.9
N.A.
N.A.
43.5
N.A.
N.A.
38
P-Site Identity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
0
93.3
0
N.A.
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
0
100
13.3
N.A.
N.A.
6.6
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
0
0
0
55
0
0
0
0
0
0
55
0
10
0
% E
% Phe:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
10
10
19
0
10
55
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
37
10
10
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
64
0
0
0
0
% K
% Leu:
0
0
19
0
10
0
19
0
55
10
10
0
0
55
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
55
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
55
0
0
10
10
0
% R
% Ser:
55
64
0
19
0
0
0
55
10
0
0
0
0
0
10
% S
% Thr:
0
0
10
0
0
10
10
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
55
0
10
0
10
0
0
0
10
0
10
0
% V
% Trp:
0
0
10
0
0
0
55
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _