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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED16
All Species:
27.88
Human Site:
S575
Identified Species:
61.33
UniProt:
Q9Y2X0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X0
NP_005472.2
877
96793
S575
F
L
N
T
P
D
K
S
P
G
D
R
L
T
E
Chimpanzee
Pan troglodytes
XP_512222
695
76224
V429
P
R
T
A
G
P
A
V
H
L
K
A
M
Q
L
Rhesus Macaque
Macaca mulatta
XP_001117192
1051
116709
S583
F
L
N
T
P
D
K
S
P
G
D
R
L
T
E
Dog
Lupus familis
XP_542212
829
91830
S563
F
L
N
T
P
D
K
S
P
G
D
R
L
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF3
828
91753
S562
F
L
N
T
P
D
K
S
P
G
D
R
L
A
E
Rat
Rattus norvegicus
NP_001100238
865
95318
S599
F
L
N
T
P
D
K
S
P
G
D
R
L
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510303
330
37309
S64
F
L
N
T
P
D
K
S
P
G
D
R
L
T
E
Chicken
Gallus gallus
XP_418220
830
92811
S564
F
L
N
T
P
D
K
S
P
G
D
R
L
T
E
Frog
Xenopus laevis
Q566H4
697
77784
L431
M
S
W
T
S
L
A
L
V
G
L
D
T
Q
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W278
818
89961
S552
F
K
S
L
L
R
P
S
D
L
G
F
Q
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177975
481
52996
L215
D
G
G
T
R
C
P
L
Q
C
F
K
V
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
77.4
88.8
N.A.
86.6
88
N.A.
32
79.4
66.2
N.A.
N.A.
26
N.A.
N.A.
25
Protein Similarity:
100
72.8
79.3
90.9
N.A.
89.8
91.1
N.A.
33.9
87.2
72.9
N.A.
N.A.
43.5
N.A.
N.A.
38
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
100
100
13.3
N.A.
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
100
100
13.3
N.A.
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
19
0
0
0
0
10
0
19
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
64
0
0
10
0
64
10
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% E
% Phe:
73
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
10
10
0
10
0
0
0
0
73
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
64
0
0
0
10
10
0
0
10
% K
% Leu:
0
64
0
10
10
10
0
19
0
19
10
0
64
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
64
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
64
10
19
0
64
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
19
0
% Q
% Arg:
0
10
0
0
10
10
0
0
0
0
0
64
0
0
0
% R
% Ser:
0
10
10
0
10
0
0
73
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
82
0
0
0
0
0
0
0
0
10
55
0
% T
% Val:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _