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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED16
All Species:
6.06
Human Site:
S707
Identified Species:
13.33
UniProt:
Q9Y2X0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X0
NP_005472.2
877
96793
S707
C
R
D
E
G
P
A
S
E
P
D
E
A
L
V
Chimpanzee
Pan troglodytes
XP_512222
695
76224
S554
K
L
F
L
I
A
I
S
S
T
L
K
S
L
L
Rhesus Macaque
Macaca mulatta
XP_001117192
1051
116709
S715
C
R
D
E
G
P
A
S
E
P
D
E
A
L
V
Dog
Lupus familis
XP_542212
829
91830
C688
L
T
K
L
W
I
C
C
R
D
E
G
P
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF3
828
91753
C687
L
T
K
L
W
I
C
C
R
D
E
G
A
A
S
Rat
Rattus norvegicus
NP_001100238
865
95318
C724
L
T
K
L
W
I
C
C
R
D
E
G
P
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510303
330
37309
C189
L
T
K
L
W
L
C
C
R
D
E
N
H
P
S
Chicken
Gallus gallus
XP_418220
830
92811
C689
L
T
K
L
W
L
C
C
R
E
E
S
H
I
T
Frog
Xenopus laevis
Q566H4
697
77784
V556
K
S
L
L
R
P
H
V
L
N
T
P
D
K
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W278
818
89961
I677
D
N
I
D
V
L
V
I
L
F
R
L
L
T
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177975
481
52996
R340
S
D
P
G
P
P
A
R
A
H
T
I
A
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
77.4
88.8
N.A.
86.6
88
N.A.
32
79.4
66.2
N.A.
N.A.
26
N.A.
N.A.
25
Protein Similarity:
100
72.8
79.3
90.9
N.A.
89.8
91.1
N.A.
33.9
87.2
72.9
N.A.
N.A.
43.5
N.A.
N.A.
38
P-Site Identity:
100
13.3
100
0
N.A.
6.6
0
N.A.
0
0
6.6
N.A.
N.A.
0
N.A.
N.A.
26.6
P-Site Similarity:
100
33.3
100
6.6
N.A.
13.3
6.6
N.A.
6.6
13.3
6.6
N.A.
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
28
0
10
0
0
0
37
19
0
% A
% Cys:
19
0
0
0
0
0
46
46
0
0
0
0
0
0
0
% C
% Asp:
10
10
19
10
0
0
0
0
0
37
19
0
10
0
0
% D
% Glu:
0
0
0
19
0
0
0
0
19
10
46
19
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
10
19
0
0
0
0
0
0
28
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
10
0
0
19
0
0
% H
% Ile:
0
0
10
0
10
28
10
10
0
0
0
10
0
10
0
% I
% Lys:
19
0
46
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
46
10
10
64
0
28
0
0
19
0
10
10
10
28
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
10
0
10
37
0
0
0
19
0
10
19
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
19
0
0
10
0
0
10
46
0
10
0
0
0
10
% R
% Ser:
10
10
0
0
0
0
0
28
10
0
0
10
10
0
46
% S
% Thr:
0
46
0
0
0
0
0
0
0
10
19
0
0
19
10
% T
% Val:
0
0
0
0
10
0
10
10
0
0
0
0
0
0
28
% V
% Trp:
0
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _