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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED16
All Species:
5.76
Human Site:
S841
Identified Species:
12.67
UniProt:
Q9Y2X0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.6
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X0
NP_005472.2
877
96793
S841
G
P
D
A
C
V
T
S
R
A
S
E
E
A
P
Chimpanzee
Pan troglodytes
XP_512222
695
76224
K662
C
G
C
V
T
M
L
K
S
P
N
R
T
T
A
Rhesus Macaque
Macaca mulatta
XP_001117192
1051
116709
S849
G
P
D
A
C
V
T
S
R
A
A
E
E
A
P
Dog
Lupus familis
XP_542212
829
91830
R796
C
G
C
V
T
M
L
R
S
P
N
K
T
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF3
828
91753
K795
C
G
C
V
T
M
L
K
S
P
N
K
T
T
A
Rat
Rattus norvegicus
NP_001100238
865
95318
K832
C
G
C
V
T
M
L
K
S
P
N
K
T
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510303
330
37309
K297
C
G
C
V
T
M
L
K
S
P
N
K
T
T
A
Chicken
Gallus gallus
XP_418220
830
92811
K797
C
G
C
V
T
M
L
K
S
P
N
K
V
T
A
Frog
Xenopus laevis
Q566H4
697
77784
Y664
K
P
S
C
L
P
V
Y
T
A
T
S
D
T
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W278
818
89961
F785
C
A
R
C
G
F
V
F
V
N
N
A
S
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177975
481
52996
G448
A
I
S
S
Q
D
K
G
P
A
E
K
L
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
77.4
88.8
N.A.
86.6
88
N.A.
32
79.4
66.2
N.A.
N.A.
26
N.A.
N.A.
25
Protein Similarity:
100
72.8
79.3
90.9
N.A.
89.8
91.1
N.A.
33.9
87.2
72.9
N.A.
N.A.
43.5
N.A.
N.A.
38
P-Site Identity:
100
0
93.3
0
N.A.
0
0
N.A.
0
0
13.3
N.A.
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
20
N.A.
20
20
N.A.
20
20
26.6
N.A.
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
19
0
0
0
0
0
37
10
10
0
19
55
% A
% Cys:
64
0
55
19
19
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
10
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
19
19
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
19
55
0
0
10
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
10
46
0
0
0
55
0
10
0
% K
% Leu:
0
0
0
0
10
0
55
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
64
0
0
0
0
% N
% Pro:
0
28
0
0
0
10
0
0
10
55
0
0
0
0
19
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
10
0
0
0
0
10
19
0
0
10
0
0
0
% R
% Ser:
0
0
19
10
0
0
0
19
55
0
10
10
10
10
0
% S
% Thr:
0
0
0
0
55
0
19
0
10
0
10
0
46
64
10
% T
% Val:
0
0
0
55
0
19
19
0
10
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _