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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED16
All Species:
4.85
Human Site:
S867
Identified Species:
10.67
UniProt:
Q9Y2X0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X0
NP_005472.2
877
96793
S867
H
S
P
R
T
P
R
S
L
D
H
L
H
P
E
Chimpanzee
Pan troglodytes
XP_512222
695
76224
W688
C
L
C
G
G
L
W
W
R
V
P
L
S
Y
P
Rhesus Macaque
Macaca mulatta
XP_001117192
1051
116709
S875
R
P
P
G
T
P
R
S
L
D
H
P
H
P
E
Dog
Lupus familis
XP_542212
829
91830
R822
C
V
C
G
G
L
W
R
R
V
P
L
S
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF3
828
91753
R821
C
L
C
G
G
L
W
R
R
V
P
L
S
C
S
Rat
Rattus norvegicus
NP_001100238
865
95318
R858
C
L
C
G
G
L
W
R
R
V
P
L
S
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510303
330
37309
R323
C
L
C
G
G
L
W
R
R
V
P
F
S
Y
S
Chicken
Gallus gallus
XP_418220
830
92811
R823
C
L
C
G
G
L
W
R
R
M
P
L
S
Y
S
Frog
Xenopus laevis
Q566H4
697
77784
P690
R
L
W
L
C
C
P
P
H
N
Q
R
L
I
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W278
818
89961
G811
K
W
L
H
C
H
C
G
G
F
W
K
Q
V
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177975
481
52996
S474
T
L
L
K
K
L
D
S
K
E
Y
V
V
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
77.4
88.8
N.A.
86.6
88
N.A.
32
79.4
66.2
N.A.
N.A.
26
N.A.
N.A.
25
Protein Similarity:
100
72.8
79.3
90.9
N.A.
89.8
91.1
N.A.
33.9
87.2
72.9
N.A.
N.A.
43.5
N.A.
N.A.
38
P-Site Identity:
100
6.6
73.3
6.6
N.A.
6.6
6.6
N.A.
0
6.6
0
N.A.
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
73.3
6.6
N.A.
6.6
6.6
N.A.
0
6.6
6.6
N.A.
N.A.
0
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
55
0
55
0
19
10
10
0
0
0
0
0
0
19
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
19
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% F
% Gly:
0
0
0
64
55
0
0
10
10
0
0
0
0
0
0
% G
% His:
10
0
0
10
0
10
0
0
10
0
19
0
19
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
0
0
10
10
0
0
0
10
0
0
10
0
0
0
% K
% Leu:
0
64
19
10
0
64
0
0
19
0
0
55
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
10
19
0
0
19
10
10
0
0
55
10
0
19
28
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
19
0
0
10
0
0
19
46
55
0
0
10
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
28
0
0
0
0
55
0
37
% S
% Thr:
10
0
0
0
19
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
10
0
0
0
0
0
0
0
46
0
10
10
10
0
% V
% Trp:
0
10
10
0
0
0
55
10
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
37
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _