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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED16
All Species:
14.55
Human Site:
T203
Identified Species:
32
UniProt:
Q9Y2X0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X0
NP_005472.2
877
96793
T203
S
G
Q
V
L
T
S
T
E
S
L
C
R
L
R
Chimpanzee
Pan troglodytes
XP_512222
695
76224
L65
L
T
R
M
I
H
I
L
D
T
E
H
P
W
D
Rhesus Macaque
Macaca mulatta
XP_001117192
1051
116709
T203
S
G
Q
V
L
T
S
T
E
S
L
C
R
L
R
Dog
Lupus familis
XP_542212
829
91830
E192
G
Q
V
L
T
S
T
E
S
L
C
R
L
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF3
828
91753
E192
G
Q
V
L
T
S
T
E
S
L
C
R
L
R
G
Rat
Rattus norvegicus
NP_001100238
865
95318
T228
S
G
Q
V
L
T
S
T
E
S
L
C
R
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510303
330
37309
Chicken
Gallus gallus
XP_418220
830
92811
T192
N
G
Q
V
L
T
S
T
E
S
L
C
R
L
R
Frog
Xenopus laevis
Q566H4
697
77784
S67
W
D
V
Y
S
I
N
S
G
H
Q
E
V
I
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W278
818
89961
V188
G
V
A
S
E
G
C
V
L
L
T
S
S
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177975
481
52996
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
77.4
88.8
N.A.
86.6
88
N.A.
32
79.4
66.2
N.A.
N.A.
26
N.A.
N.A.
25
Protein Similarity:
100
72.8
79.3
90.9
N.A.
89.8
91.1
N.A.
33.9
87.2
72.9
N.A.
N.A.
43.5
N.A.
N.A.
38
P-Site Identity:
100
0
100
0
N.A.
0
100
N.A.
0
93.3
0
N.A.
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
33.3
100
20
N.A.
20
100
N.A.
0
100
20
N.A.
N.A.
0
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
19
37
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
10
0
0
19
37
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
28
37
0
0
0
10
0
0
10
0
0
0
0
10
19
% G
% His:
0
0
0
0
0
10
0
0
0
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
10
10
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
19
37
0
0
10
10
28
37
0
19
37
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
19
37
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
19
37
19
37
% R
% Ser:
28
0
0
10
10
19
37
10
19
37
0
10
10
0
0
% S
% Thr:
0
10
0
0
19
37
19
37
0
10
10
0
0
0
10
% T
% Val:
0
10
28
37
0
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _