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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED16
All Species:
4.55
Human Site:
T515
Identified Species:
10
UniProt:
Q9Y2X0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X0
NP_005472.2
877
96793
T515
H
E
E
Y
T
R
Q
T
A
A
L
Q
Q
V
L
Chimpanzee
Pan troglodytes
XP_512222
695
76224
K369
S
L
T
N
T
D
L
K
V
A
S
D
T
Q
F
Rhesus Macaque
Macaca mulatta
XP_001117192
1051
116709
P523
D
Q
A
L
W
G
D
P
A
S
C
P
Q
V
L
Dog
Lupus familis
XP_542212
829
91830
N503
H
E
E
Y
T
R
Q
N
A
A
L
Q
Q
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF3
828
91753
K502
H
E
E
Y
T
R
Q
K
P
A
L
Q
Q
V
L
Rat
Rattus norvegicus
NP_001100238
865
95318
K539
H
E
E
Y
T
R
Q
K
P
A
L
Q
Q
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510303
330
37309
Chicken
Gallus gallus
XP_418220
830
92811
S504
H
E
E
Y
T
R
Q
S
A
A
L
Q
Q
V
L
Frog
Xenopus laevis
Q566H4
697
77784
L371
K
F
Y
P
G
L
G
L
A
L
A
F
H
D
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W278
818
89961
E492
L
L
N
L
G
N
L
E
A
L
V
E
K
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177975
481
52996
G155
F
C
M
R
P
T
Q
G
W
V
L
V
T
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
77.4
88.8
N.A.
86.6
88
N.A.
32
79.4
66.2
N.A.
N.A.
26
N.A.
N.A.
25
Protein Similarity:
100
72.8
79.3
90.9
N.A.
89.8
91.1
N.A.
33.9
87.2
72.9
N.A.
N.A.
43.5
N.A.
N.A.
38
P-Site Identity:
100
13.3
26.6
93.3
N.A.
86.6
86.6
N.A.
0
93.3
6.6
N.A.
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
40
93.3
N.A.
86.6
86.6
N.A.
0
100
6.6
N.A.
N.A.
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
55
55
10
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
10
0
0
0
0
10
0
10
0
% D
% Glu:
0
46
46
0
0
0
0
10
0
0
0
10
0
0
0
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% F
% Gly:
0
0
0
0
19
10
10
10
0
0
0
0
0
10
10
% G
% His:
46
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
28
0
0
0
0
10
0
0
% K
% Leu:
10
19
0
19
0
10
19
10
0
19
55
0
0
10
55
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
10
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
0
10
19
0
0
10
0
0
0
% P
% Gln:
0
10
0
0
0
0
55
0
0
0
0
46
55
10
0
% Q
% Arg:
0
0
0
10
0
46
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% S
% Thr:
0
0
10
0
55
10
0
10
0
0
0
0
19
0
19
% T
% Val:
0
0
0
0
0
0
0
0
10
10
10
10
0
55
0
% V
% Trp:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
10
46
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _