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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED16 All Species: 28.48
Human Site: T571 Identified Species: 62.67
UniProt: Q9Y2X0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X0 NP_005472.2 877 96793 T571 L R P H F L N T P D K S P G D
Chimpanzee Pan troglodytes XP_512222 695 76224 A425 A M K R P R T A G P A V H L K
Rhesus Macaque Macaca mulatta XP_001117192 1051 116709 T579 L R P H F L N T P D K S P G D
Dog Lupus familis XP_542212 829 91830 T559 L R P H F L N T P D K S P G D
Cat Felis silvestris
Mouse Mus musculus Q6PGF3 828 91753 T558 L R P H F L N T P D K S P G D
Rat Rattus norvegicus NP_001100238 865 95318 T595 L R P H F L N T P D K S P G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510303 330 37309 T60 L R P H F L N T P D K S P G D
Chicken Gallus gallus XP_418220 830 92811 T560 L R P H F L N T P D K S P G D
Frog Xenopus laevis Q566H4 697 77784 T427 K A L Q M S W T S L A L V G L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W278 818 89961 L548 I S T T F K S L L R P S D L G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177975 481 52996 T211 I A T S D G G T R C P L Q C F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70 77.4 88.8 N.A. 86.6 88 N.A. 32 79.4 66.2 N.A. N.A. 26 N.A. N.A. 25
Protein Similarity: 100 72.8 79.3 90.9 N.A. 89.8 91.1 N.A. 33.9 87.2 72.9 N.A. N.A. 43.5 N.A. N.A. 38
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 100 13.3 N.A. N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 100 100 13.3 N.A. N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 19 0 0 0 0 0 10 0 0 19 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 64 0 0 10 0 64 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 73 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 10 10 0 10 0 0 0 0 73 10 % G
% His: 0 0 0 64 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 0 10 0 0 0 0 64 0 0 0 10 % K
% Leu: 64 0 10 0 0 64 0 10 10 10 0 19 0 19 10 % L
% Met: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 64 0 10 0 0 0 64 10 19 0 64 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 64 0 10 0 10 0 0 10 10 0 0 0 0 0 % R
% Ser: 0 10 0 10 0 10 10 0 10 0 0 73 0 0 0 % S
% Thr: 0 0 19 10 0 0 10 82 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _