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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED16
All Species:
4.85
Human Site:
T757
Identified Species:
10.67
UniProt:
Q9Y2X0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X0
NP_005472.2
877
96793
T757
L
Q
F
G
R
A
P
T
L
P
G
S
A
A
T
Chimpanzee
Pan troglodytes
XP_512222
695
76224
Q602
T
E
G
S
F
C
H
Q
N
L
V
V
Q
R
S
Rhesus Macaque
Macaca mulatta
XP_001117192
1051
116709
T765
L
Q
F
G
R
A
P
T
L
P
G
S
A
A
T
Dog
Lupus familis
XP_542212
829
91830
L736
R
L
Q
P
K
Q
P
L
R
L
H
F
G
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGF3
828
91753
L735
R
L
Q
P
K
Q
P
L
R
L
R
F
G
R
A
Rat
Rattus norvegicus
NP_001100238
865
95318
L772
R
L
Q
P
K
Q
P
L
R
L
R
F
G
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510303
330
37309
L237
K
L
Q
G
K
Q
L
L
R
L
Q
F
G
K
P
Chicken
Gallus gallus
XP_418220
830
92811
V737
K
L
Q
N
K
Q
L
V
R
L
Q
F
G
K
A
Frog
Xenopus laevis
Q566H4
697
77784
Q604
P
T
L
Q
S
L
Q
Q
L
I
Q
W
L
G
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W278
818
89961
G725
T
T
L
L
S
A
Q
G
F
A
A
V
K
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177975
481
52996
S388
S
D
S
V
N
R
Q
S
S
S
T
Q
E
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
77.4
88.8
N.A.
86.6
88
N.A.
32
79.4
66.2
N.A.
N.A.
26
N.A.
N.A.
25
Protein Similarity:
100
72.8
79.3
90.9
N.A.
89.8
91.1
N.A.
33.9
87.2
72.9
N.A.
N.A.
43.5
N.A.
N.A.
38
P-Site Identity:
100
0
100
6.6
N.A.
6.6
6.6
N.A.
6.6
0
6.6
N.A.
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
13.3
N.A.
13.3
13.3
N.A.
13.3
6.6
6.6
N.A.
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
28
0
0
0
10
10
0
19
19
37
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
19
0
10
0
0
0
10
0
0
46
0
0
0
% F
% Gly:
0
0
10
28
0
0
0
10
0
0
19
0
46
10
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
19
0
0
0
46
0
0
0
0
0
0
0
10
28
0
% K
% Leu:
19
46
19
10
0
10
19
37
28
55
0
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
28
0
0
46
0
0
19
0
0
0
0
10
% P
% Gln:
0
19
46
10
0
46
28
19
0
0
28
10
10
0
0
% Q
% Arg:
28
0
0
0
19
10
0
0
46
0
19
0
0
28
0
% R
% Ser:
10
0
10
10
19
0
0
10
10
10
0
19
0
10
10
% S
% Thr:
19
19
0
0
0
0
0
19
0
0
10
0
0
0
19
% T
% Val:
0
0
0
10
0
0
0
10
0
0
10
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _