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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 61.21
Human Site: S145 Identified Species: 84.17
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 S145 M C L G L A H S L S R Y R L K
Chimpanzee Pan troglodytes XP_516036 529 59534 S145 M C L G L A H S L S R Y R L K
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 S145 M C L G L A H S L S R Y R L K
Dog Lupus familis XP_849592 535 60159 S145 M C L G L A H S L S R Y R L K
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 S145 M C L G L A H S L S R Y R L K
Rat Rattus norvegicus Q9QZ86 534 60052 S145 M C L G L A H S L S R Y R L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 S105 M C L G L A H S L S R Y K L K
Chicken Gallus gallus XP_421942 527 59248 S146 M C L G L A H S L S R Y K L K
Frog Xenopus laevis NP_001086628 534 59844 S146 M S L G L A H S L S R Y K L K
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 K123 N E L N I I H K F V R D K Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 S146 M A L G L A H S L S R Y K L K
Honey Bee Apis mellifera XP_395309 541 60693 S145 M A L G L A H S L S R Y K L K
Nematode Worm Caenorhab. elegans Q21276 486 54493 G118 P D L K L V F G G V I T E I L
Sea Urchin Strong. purpuratus XP_781458 535 59905 S146 M T L G L A H S L S R Y K L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 S144 M S L G L S H S L A R Y K L K
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 S146 M S L G L A H S I G R H K L K
Red Bread Mold Neurospora crassa Q8X066 597 66063 S148 M S L G L S H S L S R H K L K
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 86.6 20 N.A. 86.6 86.6 13.3 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 33.3 N.A. 93.3 93.3 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 73.3 66.6 73.3
P-Site Similarity: N.A. N.A. N.A. 93.3 86.6 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 77 0 0 0 6 0 0 0 0 0 % A
% Cys: 0 48 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 0 0 0 0 0 0 0 0 0 6 0 0 0 % D
% Glu: 0 6 0 0 0 0 0 0 0 0 0 0 6 0 0 % E
% Phe: 0 0 0 0 0 0 6 0 6 0 0 0 0 0 0 % F
% Gly: 0 0 0 89 0 0 0 6 6 6 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 95 0 0 0 0 12 0 0 0 % H
% Ile: 0 0 0 0 6 6 0 0 6 0 6 0 0 6 0 % I
% Lys: 0 0 0 6 0 0 0 6 0 0 0 0 59 0 89 % K
% Leu: 0 0 100 0 95 0 0 0 83 0 0 0 0 89 6 % L
% Met: 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 95 0 36 0 0 % R
% Ser: 0 24 0 0 0 12 0 89 0 77 0 0 0 0 6 % S
% Thr: 0 6 0 0 0 0 0 0 0 0 0 6 0 0 0 % T
% Val: 0 0 0 0 0 6 0 0 0 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 77 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _