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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 55.15
Human Site: S199 Identified Species: 75.83
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 S199 P E L G K I I S D N L T Y C K
Chimpanzee Pan troglodytes XP_516036 529 59534 S199 P E L G K I I S D N L T Y C K
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 S199 P E L G K I I S D N L T Y C K
Dog Lupus familis XP_849592 535 60159 S199 P E L G K I I S D N L T Y C K
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 S199 P E L G K I I S D N L T Y C K
Rat Rattus norvegicus Q9QZ86 534 60052 S199 P E L G K I I S D N L T Y C K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 T159 P E L G K I L T D N L T Y C K
Chicken Gallus gallus XP_421942 527 59248 T200 P E L G K I I T D N L T Y C K
Frog Xenopus laevis NP_001086628 534 59844 T200 P E L G K V I T D N L A Y C K
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 V177 L T N A T I M V V S V T A S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 T200 P E L G K I I T D N I A F V K
Honey Bee Apis mellifera XP_395309 541 60693 T199 P E L G K I I T D N I A F V K
Nematode Worm Caenorhab. elegans Q21276 486 54493 I172 H R V D N M V I Q S I A L L D
Sea Urchin Strong. purpuratus XP_781458 535 59905 T200 P E L G K I I T D N L A F A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 S198 P E L A K I I S D N I L Y A K
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 T200 P E L A K I V T D S V A Y A R
Red Bread Mold Neurospora crassa Q8X066 597 66063 P202 P E L A K I L P D N L S Y A R
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 93.3 80 13.3 N.A. 66.6 66.6 0 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 33.3 N.A. 86.6 86.6 33.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 73.3 46.6 60
P-Site Similarity: N.A. N.A. N.A. 80 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 24 0 0 0 0 0 0 0 36 6 24 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 53 0 % C
% Asp: 0 0 0 6 0 0 0 0 89 0 0 0 0 0 6 % D
% Glu: 0 89 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 18 0 0 % F
% Gly: 0 0 0 71 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 89 71 6 0 0 24 0 0 0 0 % I
% Lys: 0 0 0 0 89 0 0 0 0 0 0 0 0 0 77 % K
% Leu: 6 0 89 0 0 0 12 0 0 0 65 6 6 6 0 % L
% Met: 0 0 0 0 0 6 6 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 6 0 6 0 0 0 0 83 0 0 0 0 0 % N
% Pro: 89 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % Q
% Arg: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 12 % R
% Ser: 0 0 0 0 0 0 0 42 0 18 0 6 0 6 0 % S
% Thr: 0 6 0 0 6 0 0 42 0 0 0 53 0 0 6 % T
% Val: 0 0 6 0 0 6 12 6 6 0 12 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 71 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _