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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP58
All Species:
53.94
Human Site:
S223
Identified Species:
74.17
UniProt:
Q9Y2X3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X3
NP_057018.1
529
59578
S223
N
Y
A
S
A
K
L
S
E
L
L
P
E
E
V
Chimpanzee
Pan troglodytes
XP_516036
529
59534
S223
N
Y
A
S
A
K
L
S
E
L
L
P
E
E
V
Rhesus Macaque
Macaca mulatta
XP_001101291
530
59647
S223
N
Y
A
S
A
K
L
S
E
L
L
P
E
E
V
Dog
Lupus familis
XP_849592
535
60159
S223
N
Y
A
S
A
K
L
S
E
L
L
P
E
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6DFW4
536
60324
S223
N
Y
A
S
A
S
L
S
E
F
L
S
E
E
V
Rat
Rattus norvegicus
Q9QZ86
534
60052
S223
N
Y
A
S
A
T
L
S
E
F
L
S
E
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517321
488
54610
S183
N
F
A
S
C
D
L
S
E
I
L
P
E
E
I
Chicken
Gallus gallus
XP_421942
527
59248
S224
N
F
A
S
S
D
V
S
D
I
L
P
E
E
I
Frog
Xenopus laevis
NP_001086628
534
59844
S224
N
F
A
T
F
D
L
S
E
L
L
P
E
E
V
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
A201
E
L
Q
R
L
E
E
A
C
D
M
A
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477412
511
57152
S224
N
M
A
T
S
D
L
S
D
I
L
P
E
D
V
Honey Bee
Apis mellifera
XP_395309
541
60693
S223
N
T
I
N
S
D
L
S
D
I
L
P
E
D
V
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
Y196
G
M
R
I
R
E
W
Y
S
Y
H
Y
P
E
L
Sea Urchin
Strong. purpuratus
XP_781458
535
59905
S224
N
A
S
T
T
D
F
S
E
I
L
P
E
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
S222
N
A
A
K
L
D
F
S
E
I
L
A
D
E
I
Baker's Yeast
Sacchar. cerevisiae
Q12499
511
56938
S224
K
A
S
E
T
D
L
S
E
I
L
P
E
E
I
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
S226
N
A
T
T
A
D
L
S
E
I
L
P
H
E
I
Conservation
Percent
Protein Identity:
100
99.4
99.4
97
N.A.
94.7
95.1
N.A.
73.3
79.2
76
22.1
N.A.
61.2
60.8
38
66.7
Protein Similarity:
100
100
99.8
97.9
N.A.
96.6
96.4
N.A.
81.6
89.5
88
45.9
N.A.
75.6
75.5
56.1
81.6
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
66.6
53.3
73.3
6.6
N.A.
53.3
46.6
6.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
86.6
93.3
86.6
33.3
N.A.
86.6
80
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
48
46.5
Protein Similarity:
N.A.
N.A.
N.A.
72
67.1
62.1
P-Site Identity:
N.A.
N.A.
N.A.
40
46.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
60
66.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
65
0
42
0
0
6
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
6
0
0
0
6
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
53
0
0
18
6
0
0
6
12
0
% D
% Glu:
6
0
0
6
0
12
6
0
71
0
0
0
77
89
0
% E
% Phe:
0
18
0
0
6
0
12
0
0
12
0
0
0
0
0
% F
% Gly:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% H
% Ile:
0
0
6
6
0
0
0
0
0
48
0
0
0
0
30
% I
% Lys:
6
0
0
6
0
24
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
6
0
0
12
0
71
0
0
30
89
0
6
0
18
% L
% Met:
0
12
0
0
0
0
0
0
0
0
6
0
0
0
0
% M
% Asn:
83
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
71
6
0
0
% P
% Gln:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
6
6
6
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
12
48
18
6
0
89
6
0
0
12
0
0
0
% S
% Thr:
0
6
6
24
12
6
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
53
% V
% Trp:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
0
36
0
0
0
0
0
6
0
6
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _