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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 60.3
Human Site: S247 Identified Species: 82.92
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 S247 I S M G T E V S E E D I C N I
Chimpanzee Pan troglodytes XP_516036 529 59534 S247 I S M G T E V S E E D I C N I
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 S247 I S M G T E V S E E D I C N I
Dog Lupus familis XP_849592 535 60159 S247 I S M G T E V S E E D I C N I
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 S247 I S M G T E V S E E D I C N I
Rat Rattus norvegicus Q9QZ86 534 60052 S247 I S M G T E V S E E D I C N I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 S207 V S M G T E V S E E D I S N I
Chicken Gallus gallus XP_421942 527 59248 S248 I S M G T E V S E E D I N N I
Frog Xenopus laevis NP_001086628 534 59844 S248 I S M G T E V S E E D I N N I
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 P228 S R M S F I A P N L S I I V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 S248 I S M G T E I S E E D V L N I
Honey Bee Apis mellifera XP_395309 541 60693 S247 I S M G T E I S E D D I L N I
Nematode Worm Caenorhab. elegans Q21276 486 54493 A219 K Y S R L A V A I L D R N K M
Sea Urchin Strong. purpuratus XP_781458 535 59905 S248 I S M G T E V S Q D D I L N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 S246 I S M G T E V S D L D L L H I
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 T248 V S M G T E I T Q T D L D N I
Red Bread Mold Neurospora crassa Q8X066 597 66063 S250 I S M G T E V S E E D L Q N I
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 93.3 93.3 13.3 N.A. 80 80 13.3 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 93.3 13.3 N.A. 93.3 93.3 26.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 66.6 53.3 86.6
P-Site Similarity: N.A. N.A. N.A. 86.6 86.6 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 6 6 6 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 6 12 95 0 6 0 0 % D
% Glu: 0 0 0 0 0 89 0 0 71 65 0 0 0 0 0 % E
% Phe: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 89 0 0 0 0 0 0 0 0 0 0 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % H
% Ile: 77 0 0 0 0 6 18 0 6 0 0 71 6 0 89 % I
% Lys: 6 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % K
% Leu: 0 0 0 0 6 0 0 0 0 18 0 18 24 0 0 % L
% Met: 0 0 95 0 0 0 0 0 0 0 0 0 0 0 6 % M
% Asn: 0 0 0 0 0 0 0 0 6 0 0 0 18 83 0 % N
% Pro: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 12 0 0 0 6 0 0 % Q
% Arg: 0 6 0 6 0 0 0 0 0 0 0 6 0 0 0 % R
% Ser: 6 89 6 6 0 0 0 83 0 0 6 0 6 0 0 % S
% Thr: 0 0 0 0 89 0 0 6 0 6 0 0 0 0 0 % T
% Val: 12 0 0 0 0 0 77 0 0 0 0 6 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _