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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 33.94
Human Site: S379 Identified Species: 46.67
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 S379 Y D A F G E D S S S A M G V E
Chimpanzee Pan troglodytes XP_516036 529 59534 S379 Y D A F G E D S S S A M G V E
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 S379 Y D A F G E D S S S A M G V E
Dog Lupus familis XP_849592 535 60159 S379 Y D A F G E D S S S A M G V E
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 S379 Y D A F G E D S S S A M G I E
Rat Rattus norvegicus Q9QZ86 534 60052 S379 Y D A F G E D S S S A M G A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 S339 Y D A L G E D S S A E M G V E
Chicken Gallus gallus XP_421942 527 59248 T380 Y D A L G E D T S A E M G A E
Frog Xenopus laevis NP_001086628 534 59844 T380 Y D A L G E D T N A E L G V E
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 G366 D G Q R K K R G G R R Y R K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 A380 V D A F G E E A T F E L G A A
Honey Bee Apis mellifera XP_395309 541 60693 G379 V D A L G E D G N F D L G A E
Nematode Worm Caenorhab. elegans Q21276 486 54493 N350 R A L K T R S N T P K Y G L L
Sea Urchin Strong. purpuratus XP_781458 535 59905 A380 Y D A L G D D A S C E L G L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 Q378 V D A L G D S Q D N T M G L E
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 R380 Y D A L A E D R D D S G D I G
Red Bread Mold Neurospora crassa Q8X066 597 66063 P382 T D A L A E F P E D A D D E T
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 80 66.6 60 0 N.A. 40 46.6 6.6 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 86.6 80 86.6 6.6 N.A. 66.6 60 26.6 80
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 40 33.3 26.6
P-Site Similarity: N.A. N.A. N.A. 60 46.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 89 0 12 0 0 12 0 18 42 0 0 24 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % C
% Asp: 6 89 0 0 0 12 71 0 12 12 6 6 12 0 0 % D
% Glu: 0 0 0 0 0 77 6 0 6 0 30 0 0 6 65 % E
% Phe: 0 0 0 42 0 0 6 0 0 12 0 0 0 0 0 % F
% Gly: 0 6 0 0 77 0 0 12 6 0 0 6 83 0 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 0 0 6 6 6 0 0 0 0 6 0 0 6 0 % K
% Leu: 0 0 6 48 0 0 0 0 0 0 0 24 0 18 6 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 53 0 0 6 % M
% Asn: 0 0 0 0 0 0 0 6 12 6 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 6 0 6 0 0 0 0 0 % P
% Gln: 0 0 6 0 0 0 0 6 0 0 0 0 0 0 6 % Q
% Arg: 6 0 0 6 0 6 6 6 0 6 6 0 6 0 0 % R
% Ser: 0 0 0 0 0 0 12 42 53 36 6 0 0 0 0 % S
% Thr: 6 0 0 0 6 0 0 12 12 0 6 0 0 0 6 % T
% Val: 18 0 0 0 0 0 0 0 0 0 0 0 0 36 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 65 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _