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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP58
All Species:
30.61
Human Site:
S440
Identified Species:
42.08
UniProt:
Q9Y2X3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X3
NP_057018.1
529
59578
S440
D
S
T
L
P
T
C
S
K
K
R
K
I
E
Q
Chimpanzee
Pan troglodytes
XP_516036
529
59534
S440
D
S
T
L
P
T
C
S
K
K
R
K
I
E
Q
Rhesus Macaque
Macaca mulatta
XP_001101291
530
59647
S440
D
S
T
L
P
T
C
S
K
K
R
K
I
E
Q
Dog
Lupus familis
XP_849592
535
60159
S440
D
S
T
L
P
T
C
S
K
K
R
K
I
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6DFW4
536
60324
S440
D
S
T
L
P
T
C
S
K
K
R
K
I
E
E
Rat
Rattus norvegicus
Q9QZ86
534
60052
S440
D
S
T
L
P
T
C
S
K
K
R
K
I
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517321
488
54610
P400
D
S
T
L
P
A
F
P
K
K
R
K
F
E
E
Chicken
Gallus gallus
XP_421942
527
59248
S441
D
S
T
L
P
A
V
S
K
K
R
K
I
Q
E
Frog
Xenopus laevis
NP_001086628
534
59844
P441
D
S
T
L
P
A
V
P
K
K
R
K
F
E
E
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
T438
I
S
K
S
L
Q
R
T
L
Q
K
Q
S
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477412
511
57152
K441
D
N
T
L
N
V
K
K
K
R
K
H
S
E
S
Honey Bee
Apis mellifera
XP_395309
541
60693
K440
D
T
T
L
P
S
G
K
R
K
H
S
E
I
E
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
L411
R
Q
Q
V
E
D
R
L
E
Y
F
T
S
G
T
Sea Urchin
Strong. purpuratus
XP_781458
535
59905
P441
D
S
T
L
P
S
V
P
K
K
R
K
I
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
A439
P
A
K
T
Y
N
T
A
A
D
S
L
L
G
E
Baker's Yeast
Sacchar. cerevisiae
Q12499
511
56938
D443
A
A
S
D
S
E
S
D
S
D
D
E
E
E
E
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
S480
D
E
E
M
K
D
V
S
K
K
S
K
K
D
K
Conservation
Percent
Protein Identity:
100
99.4
99.4
97
N.A.
94.7
95.1
N.A.
73.3
79.2
76
22.1
N.A.
61.2
60.8
38
66.7
Protein Similarity:
100
100
99.8
97.9
N.A.
96.6
96.4
N.A.
81.6
89.5
88
45.9
N.A.
75.6
75.5
56.1
81.6
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
66.6
73.3
66.6
6.6
N.A.
33.3
33.3
0
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
73.3
86.6
73.3
33.3
N.A.
53.3
60
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
48
46.5
Protein Similarity:
N.A.
N.A.
N.A.
72
67.1
62.1
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
12
0
0
0
18
0
6
6
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% C
% Asp:
77
0
0
6
0
12
0
6
0
12
6
0
0
6
0
% D
% Glu:
0
6
6
0
6
6
0
0
6
0
0
6
12
65
53
% E
% Phe:
0
0
0
0
0
0
6
0
0
0
6
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
6
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
6
0
0
0
% H
% Ile:
6
0
0
0
0
0
0
0
0
0
0
0
48
6
0
% I
% Lys:
0
0
12
0
6
0
6
12
71
71
12
65
6
0
6
% K
% Leu:
0
0
0
71
6
0
0
6
6
0
0
6
6
0
0
% L
% Met:
0
0
0
6
0
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
0
6
0
0
6
6
0
0
0
0
0
0
0
0
0
% N
% Pro:
6
0
0
0
65
0
0
18
0
0
0
0
0
0
0
% P
% Gln:
0
6
6
0
0
6
0
0
0
6
0
6
0
6
24
% Q
% Arg:
6
0
0
0
0
0
12
0
6
6
59
0
0
0
0
% R
% Ser:
0
65
6
6
6
12
6
48
6
0
12
6
18
0
6
% S
% Thr:
0
6
71
6
0
36
6
6
0
0
0
6
0
0
12
% T
% Val:
0
0
0
6
0
6
24
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
0
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _