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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 29.09
Human Site: S483 Identified Species: 40
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 S483 V A E E E E T S V K K K K K R
Chimpanzee Pan troglodytes XP_516036 529 59534 S483 V S E E E E T S V K K K K K K
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 S484 V A E E E E T S V K K K K K K
Dog Lupus familis XP_849592 535 60159 S489 V V E E Q E T S V K K K K K K
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 T490 Q V V E E E P T V K K K K K K
Rat Rattus norvegicus Q9QZ86 534 60052 T488 Q V V E E E P T V K K K K K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 P441 E V E E D D T P K K K K K K K
Chicken Gallus gallus XP_421942 527 59248 P478 T N V E E D E P V K K K K K K
Frog Xenopus laevis NP_001086628 534 59844 P481 E E I E E E T P K K K K K K K
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 G470 V A F T P L Q G L E I V N P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 K473 V K S E K K K K K K K K Q K D
Honey Bee Apis mellifera XP_395309 541 60693 I491 Q S E E E V P I S K K K K K K
Nematode Worm Caenorhab. elegans Q21276 486 54493 A448 V I K K K K K A A K K A K R L
Sea Urchin Strong. purpuratus XP_781458 535 59905 S493 E T V P E P S S E K K K K K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 S477 K P E E E E P S E K K K K K K
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 E476 D S K K A K K E K K D K K E K
Red Bread Mold Neurospora crassa Q8X066 597 66063 T537 I S I K E D G T L E I L S K K
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 86.6 93.3 80 N.A. 60 60 N.A. 53.3 53.3 60 13.3 N.A. 40 53.3 26.6 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 73.3 73.3 N.A. 73.3 66.6 66.6 33.3 N.A. 60 66.6 66.6 60
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 66.6 20 13.3
P-Site Similarity: N.A. N.A. N.A. 73.3 60 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 18 0 0 6 0 0 6 6 0 0 6 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 0 6 18 0 0 0 0 6 0 0 0 6 % D
% Glu: 18 6 42 71 65 48 6 6 12 12 0 0 0 6 0 % E
% Phe: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 6 6 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 6 6 12 0 0 0 0 6 0 0 12 0 0 0 0 % I
% Lys: 6 6 12 18 12 18 18 6 24 89 83 83 83 83 77 % K
% Leu: 0 0 0 0 0 6 0 0 12 0 0 6 0 0 6 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 0 0 0 0 0 0 0 0 6 0 0 % N
% Pro: 0 6 0 6 6 6 24 18 0 0 0 0 0 6 0 % P
% Gln: 18 0 0 0 6 0 6 0 0 0 0 0 6 0 6 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 6 % R
% Ser: 0 24 6 0 0 0 6 36 6 0 0 0 6 0 0 % S
% Thr: 6 6 0 6 0 0 36 18 0 0 0 0 0 0 0 % T
% Val: 42 24 24 0 0 6 0 0 42 0 0 6 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _