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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 29.09
Human Site: S502 Identified Species: 40
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 S502 H I K E E P L S E E E P C T S
Chimpanzee Pan troglodytes XP_516036 529 59534 S502 H I K E E P L S E E E P C T S
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 S503 H I K E E P L S E E E P C T S
Dog Lupus familis XP_849592 535 60159 S508 H I K E E P L S E E E P C T S
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 S509 H I K E E P L S E E E P C T S
Rat Rattus norvegicus Q9QZ86 534 60052 S507 H I K E E P L S E E E P C T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 S459 K K V E E A A S E E E A D T T
Chicken Gallus gallus XP_421942 527 59248 T499 A E E E E E L T E E V P T S S
Frog Xenopus laevis NP_001086628 534 59844 E505 E A V E V E V E E E E P S T S
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 A486 A E K K V A E A N Q K Y F S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 P492 A V E E A A A P E P E D Q P T
Honey Bee Apis mellifera XP_395309 541 60693 E520 S F K C E K E E E K I L V T S
Nematode Worm Caenorhab. elegans Q21276 486 54493 T463 A E E S V T A T A E A E V D E
Sea Urchin Strong. purpuratus XP_781458 535 59905 E509 K V K E E P E E E E D E P E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 H509 K N K K K R K H E E E E T T E
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 E488 K E K K E K K E K K E K K E K
Red Bread Mold Neurospora crassa Q8X066 597 66063 E559 E A E E E A E E E E K P A K K
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 46.6 46.6 46.6 6.6 N.A. 20 33.3 6.6 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 53.3 66.6 53.3 46.6 N.A. 40 40 20 60
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 33.3 20 33.3
P-Site Similarity: N.A. N.A. N.A. 46.6 40 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 12 0 0 6 24 18 6 6 0 6 6 6 0 0 % A
% Cys: 0 0 0 6 0 0 0 0 0 0 0 0 36 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 6 6 6 6 0 % D
% Glu: 12 24 24 71 71 12 24 30 83 77 65 18 0 12 12 % E
% Phe: 0 6 0 0 0 0 0 0 0 0 0 0 6 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 36 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % H
% Ile: 0 36 0 0 0 0 0 0 0 0 6 0 0 0 0 % I
% Lys: 24 6 65 18 6 12 12 0 6 12 12 6 6 6 12 % K
% Leu: 0 0 0 0 0 0 42 0 0 0 0 6 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 0 0 0 0 6 0 0 0 0 0 6 % N
% Pro: 0 0 0 0 0 42 0 6 0 6 0 53 6 6 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 6 0 0 6 0 0 % Q
% Arg: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % R
% Ser: 6 0 0 6 0 0 0 42 0 0 0 0 6 12 53 % S
% Thr: 0 0 0 0 0 6 0 12 0 0 0 0 12 59 18 % T
% Val: 0 12 12 0 18 0 6 0 0 0 6 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _