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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 36.67
Human Site: S509 Identified Species: 50.42
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 S509 S E E E P C T S T A I A S P E
Chimpanzee Pan troglodytes XP_516036 529 59534 S509 S E E E P C T S T A I A S P E
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 S510 S E E E P C T S T A I A S P E
Dog Lupus familis XP_849592 535 60159 S515 S E E E P C T S T A I A S P E
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 S516 S E E E P C T S T A V P S P E
Rat Rattus norvegicus Q9QZ86 534 60052 S514 S E E E P C T S T A V P S P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 T466 S E E E A D T T E V A E T P E
Chicken Gallus gallus XP_421942 527 59248 S506 T E E V P T S S T V E N T E K
Frog Xenopus laevis NP_001086628 534 59844 S512 E E E E P S T S T A A E T P K
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 N493 A N Q K Y F S N M A E F L K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 T499 P E P E D Q P T P A K K K K K
Honey Bee Apis mellifera XP_395309 541 60693 S527 E E K I L V T S S E V S G G E
Nematode Worm Caenorhab. elegans Q21276 486 54493 E470 T A E A E V D E D A P K P K K
Sea Urchin Strong. purpuratus XP_781458 535 59905 T516 E E E D E P E T P S S E K K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 E516 H E E E E T T E T P A K K K D
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 K498 E K K E K K E K K E K K S K K
Red Bread Mold Neurospora crassa Q8X066 597 66063 K566 E E E K P A K K S K S S K R K
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 46.6 33.3 60 6.6 N.A. 20 26.6 13.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 60 60 73.3 40 N.A. 33.3 53.3 26.6 40
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 33.3 13.3 20
P-Site Similarity: N.A. N.A. N.A. 40 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 0 6 6 6 0 0 0 59 18 24 0 0 0 % A
% Cys: 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 6 6 6 0 6 0 0 0 0 0 6 % D
% Glu: 30 83 77 65 18 0 12 12 6 12 12 18 0 6 48 % E
% Phe: 0 0 0 0 0 6 0 0 0 0 0 6 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 6 6 0 % G
% His: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 6 0 0 0 0 0 0 24 0 0 0 0 % I
% Lys: 0 6 12 12 6 6 6 12 6 6 12 24 24 36 42 % K
% Leu: 0 0 0 0 6 0 0 0 0 0 0 0 6 0 0 % L
% Met: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 0 0 0 6 0 0 0 6 0 0 0 % N
% Pro: 6 0 6 0 53 6 6 0 12 6 6 12 6 48 0 % P
% Gln: 0 0 6 0 0 6 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % R
% Ser: 42 0 0 0 0 6 12 53 12 6 12 12 42 0 0 % S
% Thr: 12 0 0 0 0 12 59 18 53 0 0 0 18 0 0 % T
% Val: 0 0 0 6 0 12 0 0 0 12 18 0 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _