KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP58
All Species:
33.94
Human Site:
S514
Identified Species:
46.67
UniProt:
Q9Y2X3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X3
NP_057018.1
529
59578
S514
C
T
S
T
A
I
A
S
P
E
K
K
K
K
K
Chimpanzee
Pan troglodytes
XP_516036
529
59534
S514
C
T
S
T
A
I
A
S
P
E
K
K
K
K
K
Rhesus Macaque
Macaca mulatta
XP_001101291
530
59647
S515
C
T
S
T
A
I
A
S
P
E
K
K
K
K
K
Dog
Lupus familis
XP_849592
535
60159
S520
C
T
S
T
A
I
A
S
P
E
K
K
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6DFW4
536
60324
S521
C
T
S
T
A
V
P
S
P
E
K
K
K
K
K
Rat
Rattus norvegicus
Q9QZ86
534
60052
S519
C
T
S
T
A
V
P
S
P
E
K
K
K
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517321
488
54610
T471
D
T
T
E
V
A
E
T
P
E
K
K
K
K
K
Chicken
Gallus gallus
XP_421942
527
59248
T511
T
S
S
T
V
E
N
T
E
K
K
K
K
K
K
Frog
Xenopus laevis
NP_001086628
534
59844
T517
S
T
S
T
A
A
E
T
P
K
K
K
K
K
K
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
L498
F
S
N
M
A
E
F
L
K
V
K
R
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477412
511
57152
K504
Q
P
T
P
A
K
K
K
K
K
S
K
H
Q
E
Honey Bee
Apis mellifera
XP_395309
541
60693
G532
V
T
S
S
E
V
S
G
G
E
K
E
D
N
E
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
P475
V
D
E
D
A
P
K
P
K
K
K
K
K
S
K
Sea Urchin
Strong. purpuratus
XP_781458
535
59905
K521
P
E
T
P
S
S
E
K
K
K
K
K
K
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
K521
T
T
E
T
P
A
K
K
K
D
K
K
E
K
K
Baker's Yeast
Sacchar. cerevisiae
Q12499
511
56938
S503
K
E
K
K
E
K
K
S
K
K
E
K
K
E
K
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
K571
A
K
K
S
K
S
S
K
R
K
A
E
A
E
E
Conservation
Percent
Protein Identity:
100
99.4
99.4
97
N.A.
94.7
95.1
N.A.
73.3
79.2
76
22.1
N.A.
61.2
60.8
38
66.7
Protein Similarity:
100
100
99.8
97.9
N.A.
96.6
96.4
N.A.
81.6
89.5
88
45.9
N.A.
75.6
75.5
56.1
81.6
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
53.3
46.6
66.6
20
N.A.
13.3
26.6
33.3
26.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
66.6
66.6
80
53.3
N.A.
40
60
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
48
46.5
Protein Similarity:
N.A.
N.A.
N.A.
72
67.1
62.1
P-Site Identity:
N.A.
N.A.
N.A.
40
26.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
59
18
24
0
0
0
6
0
6
0
0
% A
% Cys:
36
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
0
6
0
0
0
0
0
6
0
0
6
0
0
% D
% Glu:
0
12
12
6
12
12
18
0
6
48
6
12
12
12
24
% E
% Phe:
6
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
6
6
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% I
% Lys:
6
6
12
6
6
12
24
24
36
42
83
83
71
71
71
% K
% Leu:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% L
% Met:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
0
0
6
0
0
0
0
0
0
6
0
% N
% Pro:
6
6
0
12
6
6
12
6
48
0
0
0
0
0
0
% P
% Gln:
6
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% Q
% Arg:
0
0
0
0
0
0
0
0
6
0
0
6
0
0
6
% R
% Ser:
6
12
53
12
6
12
12
42
0
0
6
0
0
6
0
% S
% Thr:
12
59
18
53
0
0
0
18
0
0
0
0
0
0
0
% T
% Val:
12
0
0
0
12
18
0
0
0
6
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _