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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 46.67
Human Site: T269 Identified Species: 64.17
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 T269 I E I S E Y R T Q L Y E Y L Q
Chimpanzee Pan troglodytes XP_516036 529 59534 T269 I E I S E Y R T Q L Y E Y L Q
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 T269 I E I S E Y R T Q L Y E Y L Q
Dog Lupus familis XP_849592 535 60159 T269 I E I S E Y R T Q L Y E Y L Q
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 T269 I E I S E Y R T Q L Y E Y L Q
Rat Rattus norvegicus Q9QZ86 534 60052 T269 I E I S E Y R T Q L Y E Y L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 N229 I E I S E Y R N Q L Y D Y L T
Chicken Gallus gallus XP_421942 527 59248 T270 I E I S E Y R T Q L Y D Y L K
Frog Xenopus laevis NP_001086628 534 59844 S270 I E I S E Y R S Q L Y D Y L K
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 T250 M G V A G G L T N L S K M P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 T270 I S I N D Y R T H L Y D Y L K
Honey Bee Apis mellifera XP_395309 541 60693 T269 I E I S Q Y R T Q L Y D Y L K
Nematode Worm Caenorhab. elegans Q21276 486 54493 D241 N E I L E I L D N D S E K T A
Sea Urchin Strong. purpuratus XP_781458 535 59905 T270 V E I T D Y R T Q L Y D Y L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 A268 L S L S E Y R A Q L Y D Y L K
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 E270 V E F A A Y R E Q L S N Y L S
Red Bread Mold Neurospora crassa Q8X066 597 66063 K272 I D Y S V Y R K Q L S D Y L E
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 80 86.6 80 13.3 N.A. 60 80 26.6 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 100 100 40 N.A. 86.6 100 26.6 100
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 60 46.6 53.3
P-Site Similarity: N.A. N.A. N.A. 86.6 60 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 6 0 0 6 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 0 0 12 0 0 6 0 6 0 48 0 0 0 % D
% Glu: 0 77 0 0 65 0 0 6 0 0 0 42 0 0 6 % E
% Phe: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 6 0 0 6 6 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % H
% Ile: 71 0 77 0 0 6 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 6 0 0 0 6 6 0 36 % K
% Leu: 6 0 6 6 0 0 12 0 0 95 0 0 0 89 0 % L
% Met: 6 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % M
% Asn: 6 0 0 6 0 0 0 6 12 0 0 6 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % P
% Gln: 0 0 0 0 6 0 0 0 83 0 0 0 0 0 36 % Q
% Arg: 0 0 0 0 0 0 89 0 0 0 0 0 0 0 0 % R
% Ser: 0 12 0 71 0 0 0 6 0 0 24 0 0 0 6 % S
% Thr: 0 0 0 6 0 0 0 65 0 0 0 0 0 6 6 % T
% Val: 12 0 6 0 6 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 89 0 0 0 0 77 0 89 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _