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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP58
All Species:
17.88
Human Site:
T397
Identified Species:
24.58
UniProt:
Q9Y2X3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X3
NP_057018.1
529
59578
T397
K
L
E
A
R
L
R
T
L
E
D
R
G
I
R
Chimpanzee
Pan troglodytes
XP_516036
529
59534
T397
K
L
E
A
R
L
R
T
L
E
D
R
G
I
R
Rhesus Macaque
Macaca mulatta
XP_001101291
530
59647
T397
K
L
E
A
R
L
R
T
L
E
D
R
G
I
R
Dog
Lupus familis
XP_849592
535
60159
T397
K
L
E
A
R
L
R
T
L
E
D
R
G
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6DFW4
536
60324
I397
K
L
E
A
R
L
R
I
L
E
D
R
G
I
R
Rat
Rattus norvegicus
Q9QZ86
534
60052
I397
K
L
E
A
R
L
R
I
L
E
D
R
G
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517321
488
54610
H357
K
L
E
V
R
L
R
H
L
E
E
R
G
L
R
Chicken
Gallus gallus
XP_421942
527
59248
H398
K
V
E
T
R
L
R
H
L
E
E
R
G
I
R
Frog
Xenopus laevis
NP_001086628
534
59844
H398
K
L
E
S
R
L
R
H
L
E
E
K
G
L
K
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
E395
R
M
T
F
A
E
I
E
D
D
A
Y
Q
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477412
511
57152
L398
K
L
E
S
R
L
R
L
L
E
E
G
N
L
R
Honey Bee
Apis mellifera
XP_395309
541
60693
I397
K
L
E
A
R
L
R
I
L
E
E
G
N
L
R
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
T368
S
F
I
G
K
A
G
T
K
N
K
G
R
V
S
Sea Urchin
Strong. purpuratus
XP_781458
535
59905
S398
K
M
E
S
R
L
R
S
L
E
Q
G
D
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
N396
K
L
E
A
R
L
R
N
L
E
G
K
D
L
G
Baker's Yeast
Sacchar. cerevisiae
Q12499
511
56938
Q400
K
V
E
N
R
L
S
Q
L
E
G
R
D
L
R
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
E437
A
P
K
W
D
I
K
E
A
R
K
Y
N
I
D
Conservation
Percent
Protein Identity:
100
99.4
99.4
97
N.A.
94.7
95.1
N.A.
73.3
79.2
76
22.1
N.A.
61.2
60.8
38
66.7
Protein Similarity:
100
100
99.8
97.9
N.A.
96.6
96.4
N.A.
81.6
89.5
88
45.9
N.A.
75.6
75.5
56.1
81.6
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
73.3
60
0
N.A.
60
66.6
6.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
93.3
20
N.A.
80
80
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
48
46.5
Protein Similarity:
N.A.
N.A.
N.A.
72
67.1
62.1
P-Site Identity:
N.A.
N.A.
N.A.
60
53.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
66.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
48
6
6
0
0
6
0
6
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
6
0
0
0
6
6
36
0
18
0
12
% D
% Glu:
0
0
83
0
0
6
0
12
0
83
30
0
0
12
0
% E
% Phe:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
6
0
0
6
0
0
0
12
24
53
0
6
% G
% His:
0
0
0
0
0
0
0
18
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
0
6
6
18
0
0
0
0
0
48
0
% I
% Lys:
83
0
6
0
6
0
6
0
6
0
12
12
0
0
6
% K
% Leu:
0
65
0
0
0
83
0
6
83
0
0
0
0
36
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
0
0
0
6
0
6
0
0
18
0
0
% N
% Pro:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
6
0
0
6
0
6
0
0
% Q
% Arg:
6
0
0
0
83
0
77
0
0
6
0
53
6
0
71
% R
% Ser:
6
0
0
18
0
0
6
6
0
0
0
0
0
0
6
% S
% Thr:
0
0
6
6
0
0
0
30
0
0
0
0
0
0
0
% T
% Val:
0
12
0
6
0
0
0
0
0
0
0
0
0
6
0
% V
% Trp:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _