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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP58
All Species:
21.21
Human Site:
T455
Identified Species:
29.17
UniProt:
Q9Y2X3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X3
NP_057018.1
529
59578
T455
V
D
K
E
D
E
I
T
E
K
K
A
K
K
A
Chimpanzee
Pan troglodytes
XP_516036
529
59534
T455
V
D
K
E
D
E
I
T
E
K
K
A
K
K
A
Rhesus Macaque
Macaca mulatta
XP_001101291
530
59647
T455
V
D
K
E
D
E
I
T
E
K
K
A
K
K
A
Dog
Lupus familis
XP_849592
535
60159
I455
V
D
K
E
D
E
I
I
E
K
K
A
K
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6DFW4
536
60324
T455
V
D
K
E
D
E
I
T
E
K
K
A
K
K
A
Rat
Rattus norvegicus
Q9QZ86
534
60052
T455
V
D
K
E
D
E
I
T
E
K
K
A
K
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517321
488
54610
E415
M
K
E
E
E
V
P
E
V
K
M
K
K
P
K
Chicken
Gallus gallus
XP_421942
527
59248
V456
V
E
E
Q
E
A
G
V
A
V
K
A
K
K
F
Frog
Xenopus laevis
NP_001086628
534
59844
T456
V
E
E
E
E
Q
P
T
E
I
K
V
K
A
K
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
R453
Y
G
G
K
S
T
V
R
D
R
S
S
G
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477412
511
57152
K456
E
Q
Q
T
P
V
K
K
E
E
P
A
E
E
E
Honey Bee
Apis mellifera
XP_395309
541
60693
E455
D
K
K
P
L
I
E
E
I
T
K
P
D
E
E
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
V426
V
P
K
K
N
I
D
V
M
K
E
A
E
E
A
Sea Urchin
Strong. purpuratus
XP_781458
535
59905
E456
V
N
G
D
D
E
G
E
E
T
V
S
A
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
P454
T
S
A
K
S
E
E
P
S
K
K
K
D
K
K
Baker's Yeast
Sacchar. cerevisiae
Q12499
511
56938
K458
K
K
E
K
K
E
K
K
R
K
R
D
D
D
E
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
D495
K
E
K
K
E
K
K
D
K
K
A
K
K
E
L
Conservation
Percent
Protein Identity:
100
99.4
99.4
97
N.A.
94.7
95.1
N.A.
73.3
79.2
76
22.1
N.A.
61.2
60.8
38
66.7
Protein Similarity:
100
100
99.8
97.9
N.A.
96.6
96.4
N.A.
81.6
89.5
88
45.9
N.A.
75.6
75.5
56.1
81.6
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
20
33.3
40
0
N.A.
13.3
13.3
33.3
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
40
60
66.6
40
N.A.
40
20
66.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
48
46.5
Protein Similarity:
N.A.
N.A.
N.A.
72
67.1
62.1
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
0
6
0
0
6
0
6
53
6
6
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
36
0
6
42
0
6
6
6
0
0
6
18
6
0
% D
% Glu:
6
18
24
48
24
53
12
18
53
6
6
0
12
24
18
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% F
% Gly:
0
6
12
0
0
0
12
0
0
0
0
0
6
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
36
6
6
6
0
0
0
0
0
% I
% Lys:
12
18
53
30
6
6
18
12
6
65
59
18
59
48
18
% K
% Leu:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
6
% L
% Met:
6
0
0
0
0
0
0
0
6
0
6
0
0
0
0
% M
% Asn:
0
6
0
0
6
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
6
0
6
6
0
12
6
0
0
6
6
0
6
6
% P
% Gln:
0
6
6
6
0
6
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
6
6
6
6
0
0
0
0
% R
% Ser:
0
6
0
0
12
0
0
0
6
0
6
12
0
6
6
% S
% Thr:
6
0
0
6
0
6
0
36
0
12
0
0
0
6
0
% T
% Val:
59
0
0
0
0
12
6
12
6
6
6
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _