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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 25.15
Human Site: Y217 Identified Species: 34.58
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 Y217 K V G D R K N Y A S A K L S E
Chimpanzee Pan troglodytes XP_516036 529 59534 Y217 K V G D R K N Y A S A K L S E
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 Y217 K V G D R K N Y A S A K L S E
Dog Lupus familis XP_849592 535 60159 Y217 K V G D R K N Y A S A K L S E
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 Y217 K V G D R K N Y A S A S L S E
Rat Rattus norvegicus Q9QZ86 534 60052 Y217 K V G D R K N Y A S A T L S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 F177 K V G D R Q N F A S C D L S E
Chicken Gallus gallus XP_421942 527 59248 F218 K V G D R R N F A S S D V S D
Frog Xenopus laevis NP_001086628 534 59844 F218 A V G D R I N F A T F D L S E
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 L195 T M L G D D E L Q R L E E A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 M218 L V G T R D N M A T S D L S D
Honey Bee Apis mellifera XP_395309 541 60693 T217 I I G T R E N T I N S D L S D
Nematode Worm Caenorhab. elegans Q21276 486 54493 M190 K D I N L F G M R I R E W Y S
Sea Urchin Strong. purpuratus XP_781458 535 59905 A218 H M G V R T N A S T T D F S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 A216 L M G N R V N A A K L D F S E
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 A218 T M G I R S K A S E T D L S E
Red Bread Mold Neurospora crassa Q8X066 597 66063 A220 T M G M R S N A T T A D L S E
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 73.3 60 60 0 N.A. 46.6 33.3 6.6 33.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 93.3 73.3 20 N.A. 66.6 66.6 20 53.3
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 40 33.3 46.6
P-Site Similarity: N.A. N.A. N.A. 53.3 46.6 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 0 0 0 24 65 0 42 0 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 6 % C
% Asp: 0 6 0 53 6 12 0 0 0 0 0 53 0 0 18 % D
% Glu: 0 0 0 0 0 6 6 0 0 6 0 12 6 0 71 % E
% Phe: 0 0 0 0 0 6 0 18 0 0 6 0 12 0 0 % F
% Gly: 0 0 89 6 0 0 6 0 0 0 0 0 0 0 0 % G
% His: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 6 6 6 6 0 6 0 0 6 6 0 0 0 0 0 % I
% Lys: 53 0 0 0 0 36 6 0 0 6 0 24 0 0 0 % K
% Leu: 12 0 6 0 6 0 0 6 0 0 12 0 71 0 0 % L
% Met: 0 30 0 6 0 0 0 12 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 12 0 0 83 0 0 6 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 6 0 0 6 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 89 6 0 0 6 6 6 0 0 0 0 % R
% Ser: 0 0 0 0 0 12 0 0 12 48 18 6 0 89 6 % S
% Thr: 18 0 0 12 0 6 0 6 6 24 12 6 0 0 0 % T
% Val: 0 59 0 6 0 6 0 0 0 0 0 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % W
% Tyr: 0 0 0 0 0 0 0 36 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _