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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF281 All Species: 10.3
Human Site: T848 Identified Species: 28.33
UniProt: Q9Y2X9 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X9 NP_036614.1 895 96915 T848 S G S R V P M T F I T N S N G
Chimpanzee Pan troglodytes A2T759 682 76399 G635 P Y K C S E C G K A F S Q R S
Rhesus Macaque Macaca mulatta XP_001109923 572 62874 T525 S G S R V P M T F I T N S N G
Dog Lupus familis XP_850543 879 94998 Q833 I E P R T T Y Q I E N F A Q A
Cat Felis silvestris
Mouse Mus musculus Q61624 794 88732 F748 R A G I A T Q F S T A N G Q V
Rat Rattus norvegicus Q62806 794 88729 F748 R A G I A T Q F S T A N G Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505588 1033 111229 T986 S G G R V P M T F I T N S N G
Chicken Gallus gallus XP_422106 792 88639 F746 R A G I S S Q F S T A N G Q V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A0MS83 808 90488 S762 P S S R S G I S P Q F S I A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.2 63.6 91 N.A. 32.2 32.1 N.A. 66.6 34 N.A. 34.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 30.5 63.6 92.8 N.A. 49.1 49.1 N.A. 72.5 50.5 N.A. 50.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 6.6 N.A. 6.6 6.6 N.A. 93.3 6.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 13.3 N.A. 6.6 6.6 N.A. 93.3 6.6 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 0 0 23 0 0 0 0 12 34 0 12 12 12 % A
% Cys: 0 0 0 12 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 12 0 0 0 12 0 0 0 12 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 34 34 0 23 12 0 0 0 % F
% Gly: 0 34 45 0 0 12 0 12 0 0 0 0 34 0 34 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 34 0 0 12 0 12 34 0 0 12 0 0 % I
% Lys: 0 0 12 0 0 0 0 0 12 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 12 67 0 34 0 % N
% Pro: 23 0 12 0 0 34 0 0 12 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 34 12 0 12 0 0 12 45 0 % Q
% Arg: 34 0 0 56 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 34 12 34 0 34 12 0 12 34 0 0 23 34 0 23 % S
% Thr: 0 0 0 0 12 34 0 34 0 34 34 0 0 0 0 % T
% Val: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 12 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _