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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3K All Species: 9.7
Human Site: S68 Identified Species: 21.33
UniProt: Q9Y2Y1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2Y1 NP_057394.1 108 12336 S68 N V D S T A E S C P K C E H P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q5TM50 126 13816 R86 Q G P V V D R R C P R C G H E
Dog Lupus familis XP_854405 132 14530 S92 N V D S T A E S C P K C E H P
Cat Felis silvestris
Mouse Mus musculus Q9CQZ7 108 12312 P68 N V D S T A E P C P K C E H P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520478 68 7818 C34 S T S R A P K C E H P R A Y F
Chicken Gallus gallus XP_001231486 98 10971 S64 A A W E N V D S T A E P C P K
Frog Xenopus laevis NP_001083658 108 12360 T68 N V D S T A E T C P K C A H P
Zebra Danio Brachydanio rerio NP_001002553 108 12479 P68 N V D S T A E P C P K C E H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P36958 129 15079 A89 L P R T E D H A C P K C S H R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001176546 107 12327 K67 N V D S T A E K C P K C E H P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04307 110 12495 N71 Q T K T Q C P N Y D T C G G E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 22.2 81 N.A. 98.1 N.A. N.A. 58.3 69.4 88.8 91.6 N.A. 26.3 N.A. N.A. 82.4
Protein Similarity: 100 N.A. 36.5 81.8 N.A. 99 N.A. N.A. 61.1 75.9 96.3 94.4 N.A. 41.8 N.A. N.A. 89.8
P-Site Identity: 100 N.A. 26.6 100 N.A. 93.3 N.A. N.A. 0 6.6 86.6 93.3 N.A. 33.3 N.A. N.A. 93.3
P-Site Similarity: 100 N.A. 33.3 100 N.A. 93.3 N.A. N.A. 20 20 93.3 93.3 N.A. 46.6 N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 52.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 63.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 10 55 0 10 0 10 0 0 19 0 0 % A
% Cys: 0 0 0 0 0 10 0 10 73 0 0 82 10 0 0 % C
% Asp: 0 0 55 0 0 19 10 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 10 10 0 55 0 10 0 10 0 46 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 0 19 10 0 % G
% His: 0 0 0 0 0 0 10 0 0 10 0 0 0 73 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 10 10 0 0 64 0 0 0 10 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 55 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 0 0 10 10 19 0 73 10 10 0 10 55 % P
% Gln: 19 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 10 0 0 10 10 0 0 10 10 0 0 10 % R
% Ser: 10 0 10 55 0 0 0 28 0 0 0 0 10 0 0 % S
% Thr: 0 19 0 19 55 0 0 10 10 0 10 0 0 0 0 % T
% Val: 0 55 0 10 10 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _