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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM98
All Species:
16.36
Human Site:
S122
Identified Species:
40
UniProt:
Q9Y2Y6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Y6
NP_001028676.1
226
24611
S122
S
G
A
K
M
K
T
S
A
S
V
S
D
I
I
Chimpanzee
Pan troglodytes
XP_001174579
206
22338
E106
K
I
C
H
T
L
T
E
K
L
V
A
M
T
M
Rhesus Macaque
Macaca mulatta
XP_001110487
365
37708
S261
S
G
A
K
M
K
T
S
A
S
V
S
D
I
I
Dog
Lupus familis
XP_853351
226
24482
S122
S
G
A
K
M
K
T
S
A
S
V
G
D
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91X86
226
24665
S122
S
G
A
K
M
K
T
S
A
S
V
S
D
I
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519326
114
12124
C14
V
V
V
T
E
H
S
C
V
Q
S
A
G
E
S
Chicken
Gallus gallus
XP_424353
194
20846
D94
K
R
I
S
P
R
V
D
D
V
V
R
S
M
Y
Frog
Xenopus laevis
Q6INX1
226
24574
P122
S
G
A
K
M
K
S
P
S
S
L
S
D
I
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001135933
224
23973
G120
S
N
L
T
A
I
A
G
T
V
N
S
N
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790373
245
27133
S128
N
A
H
H
P
R
T
S
D
S
L
S
D
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
59.4
96.4
N.A.
98.6
N.A.
N.A.
33.6
42
86.2
N.A.
N.A.
N.A.
32.7
N.A.
50.6
Protein Similarity:
100
91.1
60.8
97.3
N.A.
99.1
N.A.
N.A.
42.4
53
95.5
N.A.
N.A.
N.A.
53
N.A.
66.9
P-Site Identity:
100
13.3
100
93.3
N.A.
100
N.A.
N.A.
0
6.6
73.3
N.A.
N.A.
N.A.
20
N.A.
40
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
N.A.
N.A.
13.3
20
93.3
N.A.
N.A.
N.A.
26.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
50
0
10
0
10
0
40
0
0
20
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
20
0
0
0
60
0
0
% D
% Glu:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
0
0
0
10
0
0
0
10
10
0
0
% G
% His:
0
0
10
20
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
10
0
0
0
0
0
0
0
60
60
% I
% Lys:
20
0
0
50
0
50
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
10
0
0
0
10
20
0
0
0
0
% L
% Met:
0
0
0
0
50
0
0
0
0
0
0
0
10
10
10
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
20
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
20
0
0
0
0
0
10
0
0
0
% R
% Ser:
60
0
0
10
0
0
20
50
10
60
10
60
10
0
10
% S
% Thr:
0
0
0
20
10
0
60
0
10
0
0
0
0
20
0
% T
% Val:
10
10
10
0
0
0
10
0
10
20
60
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _