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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTO1 All Species: 4.85
Human Site: S251 Identified Species: 9.7
UniProt: Q9Y2Z2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2Z2 NP_001116698.1 717 79964 S251 A K E S I N F S I L N K H I P
Chimpanzee Pan troglodytes XP_527435 717 79827 N251 A K E S I N F N I L N K H I P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532202 672 74586 T237 F V V G R L K T G T P P R I A
Cat Felis silvestris
Mouse Mus musculus Q923Z3 669 74313 G237 M V G R L K T G T P P R L G K
Rat Rattus norvegicus NP_001100311 679 75393 S246 P P R L A K E S I N F S I L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506626 1086 120246 T284 R G L Q F I L T P N E F S T Q
Chicken Gallus gallus NP_001073232 646 71985 Q218 T H T N L K A Q Q I V L D N L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611677 661 73577 P233 R L K T G T P P R I A K D S V
Honey Bee Apis mellifera XP_394417 770 86576 C279 H G D S P K C C G I I L K N G
Nematode Worm Caenorhab. elegans Q20680 638 71662 G210 E L G R L R T G T P P R L M K
Sea Urchin Strong. purpuratus XP_783517 1272 137085 S292 D G R T I D Y S E L T P N H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53070 669 74197 T238 F Q L G R L K T G T P A R L A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. 84.8 N.A. 82 82.5 N.A. 44.1 62.7 N.A. N.A. N.A. 51.4 47.2 46.2 26.9
Protein Similarity: 100 99.7 N.A. 88.4 N.A. 87.3 88.5 N.A. 54.1 74 N.A. N.A. N.A. 68.1 63.3 62.2 38.8
P-Site Identity: 100 93.3 N.A. 6.6 N.A. 0 13.3 N.A. 0 0 N.A. N.A. N.A. 6.6 6.6 0 20
P-Site Similarity: 100 100 N.A. 13.3 N.A. 13.3 20 N.A. 6.6 20 N.A. N.A. N.A. 26.6 20 20 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 44.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 61.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 9 0 9 0 0 0 9 9 0 0 17 % A
% Cys: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 0 9 0 0 0 0 0 0 17 0 0 % D
% Glu: 9 0 17 0 0 0 9 0 9 0 9 0 0 0 0 % E
% Phe: 17 0 0 0 9 0 17 0 0 0 9 9 0 0 0 % F
% Gly: 0 25 17 17 9 0 0 17 25 0 0 0 0 9 17 % G
% His: 9 9 0 0 0 0 0 0 0 0 0 0 17 9 9 % H
% Ile: 0 0 0 0 25 9 0 0 25 25 9 0 9 25 0 % I
% Lys: 0 17 9 0 0 34 17 0 0 0 0 25 9 0 17 % K
% Leu: 0 17 17 9 25 17 9 0 0 25 0 17 17 17 9 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 9 0 17 0 9 0 17 17 0 9 17 0 % N
% Pro: 9 9 0 0 9 0 9 9 9 17 34 17 0 0 17 % P
% Gln: 0 9 0 9 0 0 0 9 9 0 0 0 0 0 9 % Q
% Arg: 17 0 17 17 17 9 0 0 9 0 0 17 17 0 0 % R
% Ser: 0 0 0 25 0 0 0 25 0 0 0 9 9 9 0 % S
% Thr: 9 0 9 17 0 9 17 25 17 17 9 0 0 9 0 % T
% Val: 0 17 9 0 0 0 0 0 0 0 9 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _