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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTO1 All Species: 6.36
Human Site: S561 Identified Species: 12.73
UniProt: Q9Y2Z2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2Z2 NP_001116698.1 717 79964 S561 K K L I P E A S I S T S R S L
Chimpanzee Pan troglodytes XP_527435 717 79827 S561 K K L I P E A S I S T S R S L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532202 672 74586 S525 L K S I E F S S S K W K K L I
Cat Felis silvestris
Mouse Mus musculus Q923Z3 669 74313 W527 I K F S S S K W K K L I P Q I
Rat Rattus norvegicus NP_001100311 679 75393 P535 K K L I P Q A P I S I N R S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506626 1086 120246 P861 S R L I P E L P I S L S K S V
Chicken Gallus gallus NP_001073232 646 71985 P506 L A R A I P E P L R K L A E W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611677 661 73577 W521 L R K H T H Y W R Q A L N L P
Honey Bee Apis mellifera XP_394417 770 86576 A575 Y R M F T S R A E Y R L V L R
Nematode Worm Caenorhab. elegans Q20680 638 71662 K498 E M K M S M V K W K R I I P K
Sea Urchin Strong. purpuratus XP_783517 1272 137085 P587 A F G N S K S P E K M S A M D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53070 669 74197 Q529 Q N F K L S S Q K W S S L L Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. 84.8 N.A. 82 82.5 N.A. 44.1 62.7 N.A. N.A. N.A. 51.4 47.2 46.2 26.9
Protein Similarity: 100 99.7 N.A. 88.4 N.A. 87.3 88.5 N.A. 54.1 74 N.A. N.A. N.A. 68.1 63.3 62.2 38.8
P-Site Identity: 100 100 N.A. 20 N.A. 6.6 73.3 N.A. 53.3 0 N.A. N.A. N.A. 0 0 0 6.6
P-Site Similarity: 100 100 N.A. 40 N.A. 13.3 86.6 N.A. 73.3 6.6 N.A. N.A. N.A. 6.6 20 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 44.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 61.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 9 0 0 25 9 0 0 9 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 9 0 0 0 9 25 9 0 17 0 0 0 0 9 0 % E
% Phe: 0 9 17 9 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 42 9 0 0 0 34 0 9 17 9 0 17 % I
% Lys: 25 42 17 9 0 9 9 9 17 34 9 9 17 0 9 % K
% Leu: 25 0 34 0 9 0 9 0 9 0 17 25 9 34 25 % L
% Met: 0 9 9 9 0 9 0 0 0 0 9 0 0 9 0 % M
% Asn: 0 9 0 9 0 0 0 0 0 0 0 9 9 0 0 % N
% Pro: 0 0 0 0 34 9 0 34 0 0 0 0 9 9 9 % P
% Gln: 9 0 0 0 0 9 0 9 0 9 0 0 0 9 9 % Q
% Arg: 0 25 9 0 0 0 9 0 9 9 17 0 25 0 9 % R
% Ser: 9 0 9 9 25 25 25 25 9 34 9 42 0 34 0 % S
% Thr: 0 0 0 0 17 0 0 0 0 0 17 0 0 0 0 % T
% Val: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 17 9 9 9 0 0 0 9 % W
% Tyr: 9 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _