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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTO1 All Species: 10.91
Human Site: S648 Identified Species: 21.82
UniProt: Q9Y2Z2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2Z2 NP_001116698.1 717 79964 S648 Y L T I R D V S L S H E V R E
Chimpanzee Pan troglodytes XP_527435 717 79827 S648 Y L T I R D V S L S H E V R E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532202 672 74586 D605 Q I K E V Q Q D E A L Q L P K
Cat Felis silvestris
Mouse Mus musculus Q923Z3 669 74313 E605 I K E V Q Q D E A L Q L P H E
Rat Rattus norvegicus NP_001100311 679 75393 D614 L Q L P Q D L D Y L T I K D V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506626 1086 120246 S948 Y M S I Q T V S L S H E V R E
Chicken Gallus gallus NP_001073232 646 71985 R582 Q T I G A V S R I P G V T P A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611677 661 73577 R597 R D V E D V R R E E R L S I P
Honey Bee Apis mellifera XP_394417 770 86576 S693 I E A I Y A P S I K G L Q E E
Nematode Worm Caenorhab. elegans Q20680 638 71662 S574 K Q E I D R E S A T A I P D N
Sea Urchin Strong. purpuratus XP_783517 1272 137085 K665 D L D Y T S L K L S T E A I Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53070 669 74197 Q605 N Q F V K A F Q A D E N M L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. 84.8 N.A. 82 82.5 N.A. 44.1 62.7 N.A. N.A. N.A. 51.4 47.2 46.2 26.9
Protein Similarity: 100 99.7 N.A. 88.4 N.A. 87.3 88.5 N.A. 54.1 74 N.A. N.A. N.A. 68.1 63.3 62.2 38.8
P-Site Identity: 100 100 N.A. 0 N.A. 6.6 6.6 N.A. 73.3 0 N.A. N.A. N.A. 0 20 13.3 26.6
P-Site Similarity: 100 100 N.A. 33.3 N.A. 20 20 N.A. 93.3 6.6 N.A. N.A. N.A. 0 26.6 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 44.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 61.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 17 0 0 25 9 9 0 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 0 17 25 9 17 0 9 0 0 0 17 0 % D
% Glu: 0 9 17 17 0 0 9 9 17 9 9 34 0 9 42 % E
% Phe: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 17 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 25 0 0 9 0 % H
% Ile: 17 9 9 42 0 0 0 0 17 0 0 17 0 17 0 % I
% Lys: 9 9 9 0 9 0 0 9 0 9 0 0 9 0 9 % K
% Leu: 9 25 9 0 0 0 17 0 34 17 9 25 9 9 9 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % N
% Pro: 0 0 0 9 0 0 9 0 0 9 0 0 17 17 9 % P
% Gln: 17 25 0 0 25 17 9 9 0 0 9 9 9 0 0 % Q
% Arg: 9 0 0 0 17 9 9 17 0 0 9 0 0 25 0 % R
% Ser: 0 0 9 0 0 9 9 42 0 34 0 0 9 0 0 % S
% Thr: 0 9 17 0 9 9 0 0 0 9 17 0 9 0 0 % T
% Val: 0 0 9 17 9 17 25 0 0 0 0 9 25 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 25 0 0 9 9 0 0 0 9 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _