KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTO1
All Species:
8.48
Human Site:
T612
Identified Species:
16.97
UniProt:
Q9Y2Z2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Z2
NP_001116698.1
717
79964
T612
E
R
L
K
I
E
A
T
Y
E
S
V
L
F
H
Chimpanzee
Pan troglodytes
XP_527435
717
79827
T612
E
R
L
K
I
E
A
T
Y
E
S
V
L
F
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532202
672
74586
R576
L
K
K
Y
V
E
S
R
E
L
A
E
R
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q923Z3
669
74313
A578
Y
T
A
C
R
E
L
A
R
R
L
K
I
E
A
Rat
Rattus norvegicus
NP_001100311
679
75393
T586
R
R
L
K
I
E
A
T
Y
E
S
V
L
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506626
1086
120246
I912
E
R
L
K
I
E
A
I
Y
E
T
M
I
S
L
Chicken
Gallus gallus
NP_001073232
646
71985
I557
E
D
I
D
Y
F
A
I
D
A
S
L
S
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611677
661
73577
A572
L
K
G
E
R
N
L
A
E
R
L
K
I
E
A
Honey Bee
Apis mellifera
XP_394417
770
86576
V626
I
Q
L
F
K
N
E
V
H
S
D
S
K
W
K
Nematode Worm
Caenorhab. elegans
Q20680
638
71662
R549
I
G
E
D
I
L
E
R
L
K
I
E
G
R
Y
Sea Urchin
Strong. purpuratus
XP_783517
1272
137085
P638
G
I
Y
A
P
L
I
P
Q
Q
E
A
A
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53070
669
74197
V580
L
L
D
I
P
M
H
V
V
T
K
I
N
I
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
84.8
N.A.
82
82.5
N.A.
44.1
62.7
N.A.
N.A.
N.A.
51.4
47.2
46.2
26.9
Protein Similarity:
100
99.7
N.A.
88.4
N.A.
87.3
88.5
N.A.
54.1
74
N.A.
N.A.
N.A.
68.1
63.3
62.2
38.8
P-Site Identity:
100
100
N.A.
6.6
N.A.
6.6
80
N.A.
60
20
N.A.
N.A.
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
100
N.A.
33.3
N.A.
13.3
86.6
N.A.
80
33.3
N.A.
N.A.
N.A.
20
26.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
61.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
42
17
0
9
9
9
9
9
25
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
17
0
0
0
0
9
0
9
0
0
0
0
% D
% Glu:
34
0
9
9
0
50
17
0
17
34
9
17
0
17
9
% E
% Phe:
0
0
0
9
0
9
0
0
0
0
0
0
0
17
0
% F
% Gly:
9
9
9
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
17
% H
% Ile:
17
9
9
9
42
0
9
17
0
0
9
9
25
17
0
% I
% Lys:
0
17
9
34
9
0
0
0
0
9
9
17
9
0
17
% K
% Leu:
25
9
42
0
0
17
17
0
9
9
17
9
25
17
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
17
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
17
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
9
9
0
0
0
0
9
% Q
% Arg:
9
34
0
0
17
0
0
17
9
17
0
0
9
9
0
% R
% Ser:
0
0
0
0
0
0
9
0
0
9
34
9
9
9
0
% S
% Thr:
0
9
0
0
0
0
0
25
0
9
9
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
17
9
0
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
9
0
9
9
9
0
0
0
34
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _