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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YARS2
All Species:
21.82
Human Site:
S435
Identified Species:
43.64
UniProt:
Q9Y2Z4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Z4
NP_001035526.1
477
53199
S435
M
I
T
E
G
G
V
S
I
N
H
Q
Q
V
T
Chimpanzee
Pan troglodytes
XP_528727
477
53228
S435
M
I
T
E
G
G
V
S
I
N
H
Q
Q
V
T
Rhesus Macaque
Macaca mulatta
XP_001085644
220
24795
I179
I
T
E
G
G
V
S
I
N
H
R
Q
V
T
N
Dog
Lupus familis
XP_543740
477
52762
S435
M
I
T
E
G
G
V
S
I
N
H
R
Q
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYL4
472
52579
S430
M
I
T
E
G
G
V
S
I
N
H
R
Q
V
T
Rat
Rattus norvegicus
Q5I0L3
471
52609
S429
M
I
T
E
G
G
V
S
I
N
H
R
Q
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514884
302
33702
I261
I
T
D
G
G
V
S
I
N
H
H
Q
M
T
D
Chicken
Gallus gallus
XP_416363
548
60809
S506
K
I
T
D
G
G
V
S
V
N
G
I
R
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137392
474
53427
W432
M
I
K
D
G
G
V
W
I
N
H
Q
R
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W107
464
52556
G421
A
V
R
I
I
N
A
G
G
F
Y
V
N
Q
K
Honey Bee
Apis mellifera
XP_624409
457
52620
F416
R
I
I
E
A
G
G
F
Y
I
N
Y
Q
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781450
697
77316
G655
V
G
I
I
E
D
G
G
V
Y
V
N
K
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
45.2
87.2
N.A.
85.1
84
N.A.
50.9
59.8
N.A.
60.1
N.A.
46.3
41.9
N.A.
36
Protein Similarity:
100
99.5
45.7
91.8
N.A.
89.7
89.5
N.A.
57.6
70.8
N.A.
75.8
N.A.
63.5
61
N.A.
49.5
P-Site Identity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
20
60
N.A.
60
N.A.
0
26.6
N.A.
0
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
33.3
80
N.A.
73.3
N.A.
13.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
9
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
17
0
9
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
9
50
9
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% F
% Gly:
0
9
0
17
75
67
17
17
9
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
59
0
0
0
0
% H
% Ile:
17
67
17
17
9
0
0
17
50
9
0
9
0
0
9
% I
% Lys:
9
0
9
0
0
0
0
0
0
0
0
0
9
9
9
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
50
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
17
59
9
9
9
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
42
50
17
0
% Q
% Arg:
9
0
9
0
0
0
0
0
0
0
9
25
17
0
9
% R
% Ser:
0
0
0
0
0
0
17
50
0
0
0
0
0
0
0
% S
% Thr:
0
17
50
0
0
0
0
0
0
0
0
0
0
17
50
% T
% Val:
9
9
0
0
0
17
59
0
17
0
9
9
9
50
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
9
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _