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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YARS2 All Species: 22.42
Human Site: S446 Identified Species: 44.85
UniProt: Q9Y2Z4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2Z4 NP_001035526.1 477 53199 S446 Q Q V T N P E S V L I V G Q H
Chimpanzee Pan troglodytes XP_528727 477 53228 S446 Q Q V T N P E S V L I V G Q H
Rhesus Macaque Macaca mulatta XP_001085644 220 24795 V190 Q V T N P E S V L V V G Q H I
Dog Lupus familis XP_543740 477 52762 S446 R Q V T N P E S V L V V G Q H
Cat Felis silvestris
Mouse Mus musculus Q8BYL4 472 52579 S441 R Q V T N P E S V L V I G Q H
Rat Rattus norvegicus Q5I0L3 471 52609 S440 R Q V T N P E S V L V I G Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514884 302 33702 V272 Q M T D P E S V L V L G Q H I
Chicken Gallus gallus XP_416363 548 60809 T517 I R V T N P E T V L I L G Q H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001137392 474 53427 Q443 Q R A E N P E Q V L I V G Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W107 464 52556 N432 V N Q K R V Q N I A E V L T T
Honey Bee Apis mellifera XP_624409 457 52620 E427 Y Q K I T N M E E V V V P G I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781450 697 77316 P666 N K Q R V T N P H E V L Q K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 45.2 87.2 N.A. 85.1 84 N.A. 50.9 59.8 N.A. 60.1 N.A. 46.3 41.9 N.A. 36
Protein Similarity: 100 99.5 45.7 91.8 N.A. 89.7 89.5 N.A. 57.6 70.8 N.A. 75.8 N.A. 63.5 61 N.A. 49.5
P-Site Identity: 100 100 6.6 86.6 N.A. 80 80 N.A. 6.6 73.3 N.A. 66.6 N.A. 6.6 13.3 N.A. 0
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 26.6 93.3 N.A. 73.3 N.A. 26.6 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 0 17 59 9 9 9 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 17 59 9 9 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 17 50 % H
% Ile: 9 0 0 9 0 0 0 0 9 0 34 17 0 0 25 % I
% Lys: 0 9 9 9 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 0 0 0 0 0 0 0 17 59 9 17 9 0 0 % L
% Met: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 0 9 59 9 9 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 17 59 0 9 0 0 0 0 9 0 0 % P
% Gln: 42 50 17 0 0 0 9 9 0 0 0 0 25 59 9 % Q
% Arg: 25 17 0 9 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 17 42 0 0 0 0 0 0 0 % S
% Thr: 0 0 17 50 9 9 0 9 0 0 0 0 0 9 9 % T
% Val: 9 9 50 0 9 9 0 17 59 25 50 50 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _