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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMDHD2
All Species:
40.3
Human Site:
Y118
Identified Species:
80.61
UniProt:
Q9Y303
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y303
NP_057028.2
409
43748
Y118
V
T
S
P
P
E
V
Y
H
K
V
V
P
Q
I
Chimpanzee
Pan troglodytes
XP_001163584
405
43274
Y118
V
T
S
P
P
E
V
Y
H
K
I
P
V
K
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537001
409
43838
Y118
V
T
S
P
P
E
V
Y
H
K
V
L
P
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZV7
409
43482
Y118
V
T
S
P
P
E
V
Y
H
K
V
L
P
Q
I
Rat
Rattus norvegicus
Q5BJY6
409
43520
Y118
V
T
S
P
P
E
V
Y
H
K
V
L
P
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512675
289
31055
E18
R
E
R
E
F
Q
T
E
G
V
H
L
E
G
P
Chicken
Gallus gallus
XP_001232228
409
44276
Y118
V
T
S
P
P
S
V
Y
H
Q
I
L
P
Q
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0U0
404
43667
Y118
V
T
S
P
P
H
I
Y
H
K
V
I
P
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR81
417
45264
Y132
V
T
S
P
S
D
S
Y
H
T
I
L
P
R
I
Honey Bee
Apis mellifera
XP_624337
405
44487
Y115
V
T
S
P
S
E
T
Y
H
K
I
I
P
N
I
Nematode Worm
Caenorhab. elegans
P34480
418
44869
Y129
I
T
S
S
P
E
T
Y
H
K
I
L
P
L
L
Sea Urchin
Strong. purpuratus
XP_783109
413
44836
Y121
I
T
S
S
P
D
T
Y
R
K
I
I
P
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
N.A.
92.4
N.A.
90.7
90.4
N.A.
56.9
74
N.A.
67.7
N.A.
57
57.4
49.7
57.6
Protein Similarity:
100
99
N.A.
96
N.A.
95.3
95.1
N.A.
63.5
85.8
N.A.
81.9
N.A.
73.1
74.3
67.2
71.6
P-Site Identity:
100
66.6
N.A.
93.3
N.A.
93.3
93.3
N.A.
0
73.3
N.A.
66.6
N.A.
53.3
66.6
53.3
53.3
P-Site Similarity:
100
80
N.A.
100
N.A.
100
100
N.A.
13.3
93.3
N.A.
93.3
N.A.
80
80
80
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
9
0
59
0
9
0
0
0
0
9
9
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
9
0
0
84
0
9
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
9
0
0
0
50
25
0
0
67
% I
% Lys:
0
0
0
0
0
0
0
0
0
75
0
0
0
9
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
59
0
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
75
75
0
0
0
0
0
0
9
84
0
9
% P
% Gln:
0
0
0
0
0
9
0
0
0
9
0
0
0
50
0
% Q
% Arg:
9
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% R
% Ser:
0
0
92
17
17
9
9
0
0
0
0
0
0
0
9
% S
% Thr:
0
92
0
0
0
0
34
0
0
9
0
0
0
0
0
% T
% Val:
75
0
0
0
0
0
50
0
0
9
42
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _