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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOSIP All Species: 22.73
Human Site: T174 Identified Species: 45.45
UniProt: Q9Y314 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y314 NP_057037.1 301 33172 T174 L T P E A K A T K L E K P S R
Chimpanzee Pan troglodytes XP_512823 301 33108 T174 L T P E A K A T K L E K P S R
Rhesus Macaque Macaca mulatta XP_001115348 301 33124 T174 L T P E A K A T K L E K P S R
Dog Lupus familis XP_541493 313 34339 T186 L T P E A K A T K L E K P S R
Cat Felis silvestris
Mouse Mus musculus Q9D6T0 301 33190 T174 L T P E A K A T K L E K P S R
Rat Rattus norvegicus NP_001099730 301 33239 T174 L T P E A K A T K L E K P S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NUH3 298 33285 K174 E A K T S L V K K P D K T V Y
Zebra Danio Brachydanio rerio Q5U3S7 304 33314 A174 I P S L T P E A K P T L L K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VWV8 307 34139 A180 E C P N A G L A K A Q K P D A
Honey Bee Apis mellifera XP_001120134 289 32503 Q165 E A K E T M V Q K P D K T I Y
Nematode Worm Caenorhab. elegans Q21755 310 33954 P174 G D K S T S L P S F W I P E L
Sea Urchin Strong. purpuratus XP_790354 297 33332 V173 P N A K P T L V K K P D K T V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 99.3 88.8 N.A. 90.6 91.6 N.A. N.A. N.A. 70.7 65.1 N.A. 49.8 53.1 43.8 52.4
Protein Similarity: 100 99.6 99.6 91.6 N.A. 93.3 93.3 N.A. N.A. N.A. 85.3 80.5 N.A. 66.1 70 61.2 69.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 13.3 6.6 N.A. 33.3 20 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 26.6 20 N.A. 40 26.6 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 0 59 0 50 17 0 9 0 0 0 0 9 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 17 9 0 9 0 % D
% Glu: 25 0 0 59 0 0 9 0 0 0 50 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % I
% Lys: 0 0 25 9 0 50 0 9 92 9 0 75 9 9 9 % K
% Leu: 50 0 0 9 0 9 25 0 0 50 0 9 9 0 9 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 9 59 0 9 9 0 9 0 25 9 0 67 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % R
% Ser: 0 0 9 9 9 9 0 0 9 0 0 0 0 50 0 % S
% Thr: 0 50 0 9 25 9 0 50 0 0 9 0 17 9 0 % T
% Val: 0 0 0 0 0 0 17 9 0 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _