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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEMO1
All Species:
36.36
Human Site:
Y139
Identified Species:
57.14
UniProt:
Q9Y316
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y316
NP_001131074.1
297
33733
Y139
S
I
E
M
H
L
P
Y
T
A
K
A
M
E
S
Chimpanzee
Pan troglodytes
XP_001164069
300
34275
Y142
S
I
E
M
H
L
P
Y
T
A
K
A
M
E
S
Rhesus Macaque
Macaca mulatta
XP_001105478
297
33815
Y139
S
I
E
M
H
L
P
Y
T
A
K
A
M
E
S
Dog
Lupus familis
XP_540144
385
43147
Y227
S
I
E
M
H
L
P
Y
T
A
K
A
M
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91VH6
297
33674
Y139
S
I
E
M
H
L
P
Y
T
A
K
A
M
E
S
Rat
Rattus norvegicus
Q4QQR9
297
33661
Y139
S
I
E
M
H
L
P
Y
T
A
K
A
M
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509250
289
33104
T132
I
E
M
H
L
P
Y
T
A
K
A
M
E
S
H
Chicken
Gallus gallus
XP_419531
297
33782
Y139
S
I
E
M
H
L
P
Y
T
A
K
A
M
E
S
Frog
Xenopus laevis
Q6GNT9
297
33403
Y139
S
I
E
M
H
L
P
Y
T
A
K
A
M
E
S
Zebra Danio
Brachydanio rerio
Q803S3
297
33384
Y139
S
I
E
M
H
L
P
Y
T
A
K
A
M
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650252
295
33216
K138
M
H
L
P
Y
I
A
K
V
M
E
D
Y
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22915
350
39705
F190
S
I
E
M
Q
L
P
F
I
A
K
V
M
G
S
Sea Urchin
Strong. purpuratus
XP_791245
296
33161
E139
P
Y
I
A
K
V
M
E
S
K
R
G
K
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141056
300
33471
F142
L
P
Y
L
A
K
V
F
Q
G
H
N
V
K
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47085
338
38463
E149
M
Q
L
P
M
L
V
E
T
L
K
W
R
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
94.6
75
N.A.
99.3
99.3
N.A.
85.5
97.6
90.5
88.2
N.A.
63.9
N.A.
45.7
63.6
Protein Similarity:
100
95.3
95.9
76
N.A.
100
100
N.A.
87.8
99.3
96.9
94.9
N.A.
77
N.A.
58.5
78.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
93.3
N.A.
0
N.A.
66.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
26.6
N.A.
73.3
26.6
Percent
Protein Identity:
N.A.
52.3
N.A.
N.A.
36.6
N.A.
Protein Similarity:
N.A.
66.6
N.A.
N.A.
56.2
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
7
0
7
67
7
60
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% D
% Glu:
0
7
67
0
0
0
0
14
0
0
7
0
7
67
0
% E
% Phe:
0
0
0
0
0
0
0
14
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
0
% G
% His:
0
7
0
7
60
0
0
0
0
0
7
0
0
0
7
% H
% Ile:
7
67
7
0
0
7
0
0
7
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
7
7
0
7
0
14
74
0
7
14
0
% K
% Leu:
7
0
14
7
7
74
0
0
0
7
0
0
0
0
0
% L
% Met:
14
0
7
67
7
0
7
0
0
7
0
7
67
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% N
% Pro:
7
7
0
14
0
7
67
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
7
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% R
% Ser:
67
0
0
0
0
0
0
0
7
0
0
0
0
7
60
% S
% Thr:
0
0
0
0
0
0
0
7
67
0
0
0
0
0
7
% T
% Val:
0
0
0
0
0
7
14
0
7
0
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
7
7
0
7
0
7
60
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _