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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LSM2 All Species: 39.7
Human Site: S44 Identified Species: 67.18
UniProt: Q9Y333 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y333 NP_067000.1 95 10835 S44 N I K L T D I S V T D P E K Y
Chimpanzee Pan troglodytes XP_518362 176 19302 S125 N I K L T D I S V T D P E K Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9QXA5 137 15058 I44 N I N L R E V I C T S R D G D
Rat Rattus norvegicus NP_001004073 131 14761 S80 N I K L T D I S V T D P E K Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520666 188 20509 S137 N I K L T D I S V T D P E K Y
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_571571 95 10804 S44 N I K L T D I S V T D P E K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648570 95 10719 S44 N I K L T D I S V T D P D K Y
Honey Bee Apis mellifera XP_001120188 95 10702 S44 N I K L T D I S V T D P D K Y
Nematode Worm Caenorhab. elegans NP_506348 97 11009 T44 N M K L T D I T V S D P E R F
Sea Urchin Strong. purpuratus XP_792582 95 10721 S44 N I K L T D I S V T D Q E R Y
Poplar Tree Populus trichocarpa XP_002304049 93 10689 R44 N I K L E N T R V V D Q D K Y
Maize Zea mays NP_001152698 93 10705 R44 N I K L E N T R V V D Q D K Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_563682 93 10676 R44 N I K L E N T R V V D Q D K Y
Baker's Yeast Sacchar. cerevisiae P38203 95 11144 S44 N L K L D N I S C T D E K K Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.9 N.A. N.A. N.A. 22.6 72.5 N.A. 50.5 N.A. N.A. 98.9 N.A. 91.5 92.6 82.4 90.5
Protein Similarity: 100 53.9 N.A. N.A. N.A. 39.4 72.5 N.A. 50.5 N.A. N.A. 98.9 N.A. 95.7 95.7 93.8 93.6
P-Site Identity: 100 100 N.A. N.A. N.A. 26.6 100 N.A. 100 N.A. N.A. 100 N.A. 93.3 93.3 66.6 86.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 46.6 100 N.A. 100 N.A. N.A. 100 N.A. 100 100 100 93.3
Percent
Protein Identity: 70.5 69.4 N.A. 71.5 63.1 N.A.
Protein Similarity: 81 80 N.A. 82.1 81 N.A.
P-Site Identity: 53.3 53.3 N.A. 53.3 60 N.A.
P-Site Similarity: 66.6 66.6 N.A. 66.6 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 65 0 0 0 0 93 0 43 0 8 % D
% Glu: 0 0 0 0 22 8 0 0 0 0 0 8 50 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 86 0 0 0 0 72 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 93 0 0 0 0 0 0 0 0 0 8 79 0 % K
% Leu: 0 8 0 100 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 100 0 8 0 0 29 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 58 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 29 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 22 0 0 0 8 0 15 0 % R
% Ser: 0 0 0 0 0 0 0 65 0 8 8 0 0 0 0 % S
% Thr: 0 0 0 0 65 0 22 8 0 72 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 86 22 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _